Tumor suppressive pathways in the control of neurogenesis

Bmi1 Is Required for Hedgehog Pathway-Driven Medulloblastoma Expansion

(2015) Lowell Evan Michael et al.   NEOPLASIA

RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3

(2012) Lígia Tavares et al.   CELL

Polycomb Associates Genome-wide with a Specific RNA Polymerase II Variant, and Regulates Metabolic Genes in ESCs

(2012) Emily Brookes et al.   Cell Stem Cell

Calcium-Dependent Dephosphorylation of the Histone Chaperone DAXX Regulates H3.3 Loading and Transcription upon Neuronal Activation

(2012) David Michod et al.   NEURON

Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma

(2011) Chong Liu et al.   CELL

DeltaNp73 transcription factors modulate cell survival and tumor development

(2011) Aurélia Ravni et al.   CELL CYCLE

While p73 is essential, p63 is completely dispensable for the development of the central nervous system

(2011) Lena Holembowski et al.   CELL CYCLE

Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner

(2011) Janel E. Le Belle et al.   Cell Stem Cell

p53 coordinates cranial neural crest cell growth and epithelial-mesenchymal transition/delamination processes

(2011) A. Rinon et al.   DEVELOPMENT

Roles of p53 and p27 Kip1 in the regulation of neurogenesis in the murine adult subventricular zone

(2011) Sara Gil-Perotin et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Overexpression of cdk4 and cyclinD1 triggers greater expansion of neural stem cells in the adult mouse brain

(2011) Benedetta Artegiani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

 Np63 Regulates Stem Cell Dynamics in the Mammalian Olfactory Epithelium

(2011) A. Packard et al.   JOURNAL OF NEUROSCIENCE

p63 Regulates Olfactory Stem Cell Self-Renewal and Differentiation

(2011) Russell B. Fletcher et al.   NEURON

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions

(2011) Guo-li Ming et al.   NEURON

Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets

(2011) M. Agostini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cdk6-Dependent Regulation of G1 Length Controls Adult Neurogenesis

(2011) Pierre Beukelaers et al.   STEM CELLS

PML/RARA Oxidation and Arsenic Binding Initiate the Antileukemia Response of As2O3

(2010) Marion Jeanne et al.   CANCER CELL

Cdks and cyclins link G1length and differentiation of embryonic, neural and hematopoietic stem cells

(2010) Christian Lange et al.   CELL CYCLE

p53 stabilization: the importance of nuclear import

(2010) J-C Marine   CELL DEATH AND DIFFERENTIATION

A Distinctive DNA Damage Response in Human Hematopoietic Stem Cells Reveals an Apoptosis-Independent Role for p53 in Self-Renewal

(2010) Michael Milyavsky et al.   Cell Stem Cell

TAp73 Acts via the bHLH Hey2 to Promote Long-Term Maintenance of Neural Precursors

(2010) Masashi Fujitani et al.   CURRENT BIOLOGY

Autophagy regulation by p53

(2010) Maria Chiara Maiuri et al.   CURRENT OPINION IN CELL BIOLOGY

Continuous neurogenesis in the adult brain

(2010) Itaru Imayoshi et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive

(2010) C. H. Coschi et al.   GENES & DEVELOPMENT

The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3

(2010) P. Drane et al.   GENES & DEVELOPMENT

Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling

(2010) T. van Harn et al.   GENES & DEVELOPMENT

RB's original CIN?

(2010) J. Sage et al.   GENES & DEVELOPMENT

Isoform-specific p73 knockout mice reveal a novel role for  Np73 in the DNA damage response pathway

(2010) M. T. Wilhelm et al.   GENES & DEVELOPMENT

Bmi1 directly represses p21Waf1/Cip1 in Shh-induced proliferation of cerebellar granule cell progenitors

(2010) T. Subkhankulova et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The Role of PML in the Nervous System

(2010) Paolo Salomoni et al.   MOLECULAR NEUROBIOLOGY

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

(2010) P. W. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arsenic Trioxide Controls the Fate of the PML-RAR  Oncoprotein by Directly Binding PML

(2010) X. W. Zhang et al.   SCIENCE

p53 and stem cells: new developments and new concerns

(2010) Tongbiao Zhao et al.   TRENDS IN CELL BIOLOGY

Cell cycle control of mammalian neural stem cells: putting a speed limit on G1

(2010) Paolo Salomoni et al.   TRENDS IN CELL BIOLOGY

PML Nuclear Bodies

(2010) V. Lallemand-Breitenbach et al.   Cold Spring Harbor Perspectives in Biology

p53 Research: The Past Thirty Years and the Next Thirty Years

(2010) D. Lane et al.   Cold Spring Harbor Perspectives in Biology

p63 and p73, the Ancestors of p53

(2010) V. Dotsch et al.   Cold Spring Harbor Perspectives in Biology

Mechanisms of Stem Cell Self-Renewal

(2009) He Shenghui et al.   Annual Review of Cell and Developmental Biology

The Glial Nature of Embryonic and Adult Neural Stem Cells

(2009) Arnold Kriegstein et al.   Annual Review of Neuroscience

Expression of Mutant p53 Proteins Implicates a Lineage Relationship between Neural Stem Cells and Malignant Astrocytic Glioma in a Murine Model

(2009) Yuan Wang et al.   CANCER CELL

Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model

(2009) Sheila Alcantara Llaguno et al.   CANCER CELL

Retinoblastoma Has Properties of a Cone Precursor Tumor and Depends Upon Cone-Specific MDM2 Signaling

(2009) Xiaoliang L. Xu et al.   CELL

Cdk4/CyclinD1 Overexpression in Neural Stem Cells Shortens G1, Delays Neurogenesis, and Promotes the Generation and Expansion of Basal Progenitors

(2009) Christian Lange et al.   Cell Stem Cell

Home at Last: Neural Stem Cell Niches Defined

(2009) Freda D. Miller et al.   Cell Stem Cell

Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes

(2009) Thomas S Jacques et al.   EMBO JOURNAL

Perspectives in PML: a unifying framework for PML function

(2009) Katherine et al.   Frontiers in Bioscience-Landmark

PML links aberrant cytokine signaling and oncogenic stress to cellular senescence

(2009) Veronique Bourdeau   Frontiers in Bioscience-Landmark

Cell type specificity of PI3K signaling in Pdk1- and Pten-deficient brains

(2009) N. Chalhoub et al.   GENES & DEVELOPMENT

Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain

(2009) C. A. Fasano et al.   GENES & DEVELOPMENT

p27KIP1 Regulates Neurogenesis in the Rostral Migratory Stream and Olfactory Bulb of the Postnatal Mouse

(2009) X. Li et al.   JOURNAL OF NEUROSCIENCE

The Polycomb Group Gene Bmi1 Regulates Antioxidant Defenses in Neurons by Repressing p53 Pro-Oxidant Activity

(2009) W. Chatoo et al.   JOURNAL OF NEUROSCIENCE

p63 Antagonizes p53 to Promote the Survival of Embryonic Neural Precursor Cells

(2009) C. B. Dugani et al.   JOURNAL OF NEUROSCIENCE

BMI1 Sustains Human Glioblastoma Multiforme Stem Cell Renewal

(2009) M. Abdouh et al.   JOURNAL OF NEUROSCIENCE

The p107/E2F Pathway Regulates Fibroblast Growth Factor 2 Responsiveness in Neural Precursor Cells

(2009) K. A. McClellan et al.   MOLECULAR AND CELLULAR BIOLOGY

Bmi1 regulates mitochondrial function and the DNA damage response pathway

(2009) Jie Liu et al.   NATURE

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

The tumor suppressor Pml regulates cell fate in the developing neocortex

(2009) Tarik Regad et al.   NATURE NEUROSCIENCE

PML depletion disrupts normal mammary gland development and skews the composition of the mammary luminal cell progenitor pool

(2009) W. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DeltaNp73 regulates neuronal survival in vivo

(2009) F. Tissir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity

(2009) Richard Tomasini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Origins and Evolution of the p53 Family of Genes

(2009) V. A. Belyi et al.   Cold Spring Harbor Perspectives in Biology

Copy number alterations of the polycomb gene BMI1 in gliomas

(2008) Valtteri Häyry et al.   ACTA NEUROPATHOLOGICA

New insights into the role of PML in tumour suppression

(2008) P Salomoni et al.   CELL RESEARCH

Neural Stem Cells Confer Unique Pinwheel Architecture to the Ventricular Surface in Neurogenic Regions of the Adult Brain

(2008) Zaman Mirzadeh et al.   Cell Stem Cell

A Specialized Vascular Niche for Adult Neural Stem Cells

(2008) Masoud Tavazoie et al.   Cell Stem Cell

Adult SVZ Stem Cells Lie in a Vascular Niche: A Quantitative Analysis of Niche Cell-Cell Interactions

(2008) Qin Shen et al.   Cell Stem Cell

CDK Inhibitors: Cell Cycle Regulators and Beyond

(2008) Arnaud Besson et al.   DEVELOPMENTAL CELL

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

(2008) R. Tomasini et al.   GENES & DEVELOPMENT

PML targeting eradicates quiescent leukaemia-initiating cells

(2008) Keisuke Ito et al.   NATURE

p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

(2008) Hongwu Zheng et al.   NATURE

Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain

(2008) Itaru Imayoshi et al.   NATURE NEUROSCIENCE

Transcriptional control of human p53-regulated genes

(2008) Todd Riley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stem cell protein BMI-1 is an independent marker for poor prognosis in oligodendroglial tumours

(2008) V. Häyry et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Expression of the Polycomb-Group Protein BMI1 and correlation with p16 in astrocytomas

(2008) Roberto Tirabosco et al.   PATHOLOGY RESEARCH AND PRACTICE

p21Cip1 restricts neuronal proliferation in the subgranular zone of the dentate gyrus of the hippocampus

(2008) R. N. Pechnick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regenerative capacity of neural precursors in the adult mammalian brain is under the control of p53

(2007) Silvia Medrano et al.   NEUROBIOLOGY OF AGING