The Fanconi anemia pathway in replication stress and DNA crosslink repair

FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway

(2012) A. M. Ali et al.   BLOOD

Regulation of Rev1 by the Fanconi anemia core complex

(2012) Hyungjin Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI

(2012) K. Sato et al.   NUCLEIC ACIDS RESEARCH

Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair

(2012) J. W. C. Leung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI

(2011) S. A. Williams et al.   BLOOD

Selective Bypass of a Lagging Strand Roadblock by the Eukaryotic Replicative DNA Helicase

(2011) Yu V. Fu et al.   CELL

Orchestrating the nucleases involved in DNA interstrand cross-link (ICL) repair

(2011) Blanka Sengerová et al.   CELL CYCLE

Insights into phosphorylation-dependent mechanisms regulating USP1 protein stability during the cell cycle

(2011) Xiomaris M. Cotto Rios et al.   CELL CYCLE

Dysregulation of DNA polymerase κ recruitment to replication forks results in genomic instability

(2011) Mathew JK Jones et al.   EMBO JOURNAL

APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage

(2011) Xiomaris M. Cotto-Rios et al.   JOURNAL OF CELL BIOLOGY

The USP1/UAF1 Complex Promotes Double-Strand Break Repair through Homologous Recombination

(2011) J. Murai et al.   MOLECULAR AND CELLULAR BIOLOGY

Stalled Fork Rescue via Dormant Replication Origins in Unchallenged S Phase Promotes Proper Chromosome Segregation and Tumor Suppression

(2011) Tsuyoshi Kawabata et al.   MOLECULAR CELL

Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site

(2011) Anne Letessier et al.   NATURE

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

(2011) Claudia Lukas et al.   NATURE CELL BIOLOGY

Homology-directed Fanconi anemia pathway cross-link repair is dependent on DNA replication

(2011) Koji Nakanishi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of the activation of the Fanconi anemia pathway by the p21 cyclin-dependent kinase inhibitor

(2011) M A Rego et al.   ONCOGENE

Replication-Fork Stalling and Processing at a Single Psoralen Interstrand Crosslink in Xenopus Egg Extracts

(2011) Cyrille Le Breton et al.   PLoS One

Mechanism of RAD51-Dependent DNA Interstrand Cross-Link Repair

(2011) D. T. Long et al.   SCIENCE

Structure of the FANCI-FANCD2 Complex: Insights into the Fanconi Anemia DNA Repair Pathway

(2011) Woo Joo et al.   SCIENCE

Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repair

(2010) L. Colnaghi et al.   BLOOD

Identification of KIAA1018/FAN1, a DNA Repair Nuclease Recruited to DNA Damage by Monoubiquitinated FANCD2

(2010) Craig MacKay et al.   CELL

Deficiency of FANCD2-Associated Nuclease KIAA1018/FAN1 Sensitizes Cells to Interstrand Crosslinking Agents

(2010) Katja Kratz et al.   CELL

Human KIAA1018/FAN1 localizes to stalled replication forks via its ubiquitin-binding domain

(2010) Robert D. Shereda et al.   CELL CYCLE

The Fanconi anemia pathway and ICL repair: implications for cancer therapy

(2010) Lily C Wang et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Physical and functional crosstalk between Fanconi anemia core components and the GINS replication complex

(2010) Emanuela Tumini et al.   DNA REPAIR

Expanded roles of the Fanconi anemia pathway in preserving genomic stability

(2010) Y. Kee et al.   GENES & DEVELOPMENT

RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network

(2010) Liyi Geng et al.   JOURNAL OF CELL BIOLOGY

A Genetic Screen Identifies FAN1, a Fanconi Anemia-Associated Nuclease Necessary for DNA Interstrand Crosslink Repair

(2010) Agata Smogorzewska et al.   MOLECULAR CELL

Mutation of the RAD51C gene in a Fanconi anemia–like disorder

(2010) Fiona Vaz et al.   NATURE GENETICS

Eukaryotic DNA replication origins: many choices for appropriate answers

(2010) Marcel Méchali   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

(2010) Mary Ellen Moynahan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FAN1 Acts with FANCI-FANCD2 to Promote DNA Interstrand Cross-Link Repair

(2010) T. Liu et al.   SCIENCE

How the Fanconi Anemia Pathway Guards the Genome

(2009) George-Lucian Moldovan et al.   Annual Review of Genetics

Inactivation of Murine Usp1 Results in Genomic Instability and a Fanconi Anemia Phenotype

(2009) Jung Min Kim et al.   DEVELOPMENTAL CELL

Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen

(2009) Asami Hishiki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Repair of Laser-localized DNA Interstrand Cross-links in G1Phase Mammalian Cells

(2009) Parameswary A. Muniandy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Interaction between the Fanconi Anemia D2 Protein and Proliferating Cell Nuclear Antigen (PCNA) via a Conserved Putative PCNA Interaction Motif

(2009) Niall G. Howlett et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA Polymerase POLN Participates in Cross-Link Repair and Homologous Recombination

(2009) G.-L. Moldovan et al.   MOLECULAR AND CELLULAR BIOLOGY

Checkpoint Signaling from a Single DNA Interstrand Crosslink

(2009) Merav Ben-Yehoyada et al.   MOLECULAR CELL

Recruitment of Fanconi Anemia and Breast Cancer Proteins to DNA Damage Sites Is Differentially Governed by Replication

(2009) Xi Shen et al.   MOLECULAR CELL

Replication stress induces sister-chromatid bridging at fragile site loci in mitosis

(2009) Kok Lung Chan et al.   NATURE CELL BIOLOGY

The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities

(2009) Valeria Naim et al.   NATURE CELL BIOLOGY

The Fanconi Anemia Pathway Promotes Replication-Dependent DNA Interstrand Cross-Link Repair

(2009) P. Knipscheer et al.   SCIENCE

Structural and Functional Relationships of the XPF/MUS81 Family of Proteins

(2008) Alberto Ciccia et al.   Annual Review of Biochemistry

Distortion-Dependent Unhooking of Interstrand Cross-Links in Mammalian Cell Extracts†

(2008) Michael B. Smeaton et al.   BIOCHEMISTRY

Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24

(2008) J. M. Kim et al.   BLOOD

Mechanism of Replication-Coupled DNA Interstrand Crosslink Repair

(2008) Markus Räschle et al.   CELL

The Fanconi anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly

(2008) Kanchan D. Mirchandani et al.   DNA REPAIR

Role for DNA Polymerase κ in the Processing ofN2-N2-Guanine Interstrand Cross-links

(2008) Irina G. Minko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Fanconi Anemia Protein FANCM Can Promote Branch Migration of Holliday Junctions and Replication Forks

(2008) Kerstin Gari et al.   MOLECULAR CELL

Mechanistic Insight into Site-Restricted Monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI

(2008) Arno F. Alpi et al.   MOLECULAR CELL

The genetic and molecular basis of Fanconi anemia

(2008) Johan P. de Winter et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Remodeling of DNA replication structures by the branch point translocase FANCM

(2008) K. Gari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA polymerase η reduces the γ-H2AX response to psoralen interstrand crosslinks in human cells

(2007) Seiki Mogi et al.   EXPERIMENTAL CELL RESEARCH