Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects

Cutting Edge: Instructive Role of Peripheral Tissue Cells in the Imprinting of T Cell Homing Receptor Patterns

(2014) F. Edele et al.   JOURNAL OF IMMUNOLOGY

Langerin Expressing Cells Promote Skin Immune Responses under Defined Conditions

(2014) L. Wang et al.   JOURNAL OF IMMUNOLOGY

Skin sensitisation: the Colipa strategy for developing and evaluating non-animal test methods for risk assessment

(2014) Gavin Maxwell   ALTEX-Alternatives to Animal Experimentation

CD4+CD25+ and CD4+CD25high regulatory T cells in disseminated and localized forms of allergic contact dermatitis: relation to specific cytokines

(2013) Teresa Reduta et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Mechanisms of chemical-induced innate immunity in allergic contact dermatitis

(2011) S. F. Martin et al.   ALLERGY

Active transport of contact allergens in human monocyte-derived dendritic cells is mediated by multidrug resistance related proteins

(2011) Claudia Skazik et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A genomic biomarker signature can predict skin sensitizers using a cell-based in vitro alternative to animal tests

(2011) Henrik Johansson et al.   BMC GENOMICS

Nickel allergy is still frequent in young German females - probably because of insufficient protection from nickel-releasing objects

(2011) Axel Schnuch et al.   CONTACT DERMATITIS

IL-33 Activates B1 Cells and Exacerbates Contact Sensitivity

(2011) M. Komai-Koma et al.   JOURNAL OF IMMUNOLOGY

Evaluating the sensitization potential of surfactants: Integrating data from the local lymph node assay, guinea pig maximization test, and in vitro methods in a weight-of-evidence approach

(2011) Nicholas Ball et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

T-cell recognition of chemicals, protein allergens and drugs: towards the development of in vitro assays

(2010) Stefan F. Martin et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Trends of contact allergy to fragrance mix I and Myroxylon pereirae among Danish eczema patients tested between 1985 and 2007*

(2010) Jacob P. Thyssen et al.   CONTACT DERMATITIS

Linalool - a significant contact sensitizer after air exposure

(2010) Johanna Bråred Christensson et al.   CONTACT DERMATITIS

Patch testing with fragrance mix II: results of the IVDK 2005-2008

(2010) Andrea Krautheim et al.   CONTACT DERMATITIS

Genetic factors in contact allergy-review and future goals

(2010) Axel Schnuch et al.   CONTACT DERMATITIS

Contact allergy to essential oils: current patch test results (2000-2008) from the Information Network of Departments of Dermatology (IVDK)*

(2010) Wolfgang Uter et al.   CONTACT DERMATITIS

Contact allergy to fragrances: current patch test results (2005-2008) from the Information Network of Departments of Dermatology*

(2010) Wolfgang Uter et al.   CONTACT DERMATITIS

Standardized tape stripping prior to patch testing induces upregulation of Hsp90, Hsp70, IL-33, TNF-α and IL-8/CXCL8 mRNA: new insights into the involvement of ‘alarmins’

(2010) Heinrich Dickel et al.   CONTACT DERMATITIS

Occupational contact allergy in the building trade in Germany: influence of preventive measures and changing exposure

(2010) Johannes Geier et al.   INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH

Gap junctions between regulatory T cells and dendritic cells prevent sensitization of CD8+ T cells

(2010) Sabine Ring et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Inducible costimulator (ICOS) is a marker for highly suppressive antigen-specific T cells sharing features of TH17/TH1 and regulatory T cells

(2010) Marc Vocanson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice

(2010) Michio Tomura et al.   JOURNAL OF CLINICAL INVESTIGATION

Enhanced murine contact hypersensitivity by depletion of endogenous regulatory T cells in the sensitization phase

(2010) Tetsuya Honda et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Lack of the purinergic receptor P2X7results in resistance to contact hypersensitivity

(2010) Felix C. Weber et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ATP Activates Regulatory T Cells In Vivo during Contact Hypersensitivity Reactions

(2010) S. Ring et al.   JOURNAL OF IMMUNOLOGY

Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel

(2010) Marc Schmidt et al.   NATURE IMMUNOLOGY

Critical role for the chemokine receptor CXCR6 in NK cell–mediated antigen-specific memory of haptens and viruses

(2010) Silke Paust et al.   NATURE IMMUNOLOGY

High-Resolution Transcriptional Profiling of Chemical-Stimulated Dendritic Cells Identifies Immunogenic Contact Allergens, but Not Prohaptens

(2010) H. Ott et al.   SKIN PHARMACOLOGY AND PHYSIOLOGY

Assessment of Chemical Skin-Sensitizing Potency by an In Vitro Assay Based on Human Dendritic Cells

(2010) Nathalie Lambrechts et al.   TOXICOLOGICAL SCIENCES

Effector and regulatory mechanisms in allergic contact dermatitis

(2009) M. Vocanson et al.   ALLERGY

Para-phenylenediamine and allergic sensitization: risk modification byN-acetyltransferase 1 and 2 genotypes

(2009) B. Blömeke et al.   BRITISH JOURNAL OF DERMATOLOGY

Cutaneous Metabolic Activation of Carvoxime, a Self-Activating, Skin-Sensitizing Prohapten

(2009) Hagen Ott et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Air oxidation increases skin irritation from fragrance terpenes

(2009) Johanna Bråred Christensson et al.   CONTACT DERMATITIS

Nothing is perfect, not even the local lymph node assay: a commentary and the implications for REACH

(2009) David A. Basketter et al.   CONTACT DERMATITIS

Dendritic cells: biology of the skin

(2009) Mascha J. Toebak et al.   CONTACT DERMATITIS

TLR2-activated human langerhans cells promote Th17 polarization via IL-1β, TGF-β and IL-23

(2009) Ehsan Aliahmadi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD4+CD25+ regulatory T cells suppress contact hypersensitivity reactions through a CD39, adenosine-dependent mechanism

(2009) Sabine Ring et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CD56highCD16-CD62L- NK Cells Accumulate in Allergic Contact Dermatitis and Contribute to the Expression of Allergic Responses

(2009) T. Carbone et al.   JOURNAL OF IMMUNOLOGY

Keratinocytes Function as Accessory Cells for Presentation of Endogenous Antigen Expressed in the Epidermis

(2009) Brian S. Kim et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Natural Killer T Cells: An Unconventional T-Cell Subset with Diverse Effector and Regulatory Functions

(2009) Anna Balato et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells

(2009) Sara Trifari et al.   NATURE IMMUNOLOGY

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

(2009) Thomas Duhen et al.   NATURE IMMUNOLOGY

Interleukin-33 – cytokine of dual function or novel alarmin?

(2009) Guttorm Haraldsen et al.   TRENDS IN IMMUNOLOGY

para-Phenylenediamine: the profile of an important allergen. Results of the IVDK1

(2008) A. Schnuch et al.   BRITISH JOURNAL OF DERMATOLOGY

Loss-of-function polymorphisms in the filaggrin gene are associated with an increased susceptibility to chronic irritant contact dermatitis: a case-control study

(2008) C.M. de Jongh et al.   BRITISH JOURNAL OF DERMATOLOGY

The balance between immunity and tolerance: The role of Langerhans cells

(2008) K. Mutyambizi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The outcome of dimethylglyoxime testing in a sample of cell phones in Denmark

(2008) Jacob Pontoppidan Thyssen et al.   CONTACT DERMATITIS

Decreasing trends in methyldibromo glutaronitrile contact allergy – following regulatory intervention

(2008) Jeanne D Johansen et al.   CONTACT DERMATITIS

Hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral®) is still a frequent allergen

(2008) P. Braendstrup et al.   CONTACT DERMATITIS

Epidemiological data on consumer allergy top-phenylenediamine

(2008) Jacob Pontoppidan Thyssen et al.   CONTACT DERMATITIS

Lavender oil lacks natural protection against autoxidation, forming strong contact allergens on air exposure

(2008) Lina Hagvall et al.   CONTACT DERMATITIS

Deposition of nickel, chromium, and cobalt on the skin in some occupations – assessment by acid wipe sampling

(2008) Carola Lidén et al.   CONTACT DERMATITIS

Expression and Function of Cytochrome P450-Dependent Enzymes in Human Skin Cells

(2008) J. Baron et al.   CURRENT MEDICINAL CHEMISTRY

Der dreistufige Hautschutzplan

(2008) B Kütting et al.   DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT

Differential expression of influx and efflux transport proteins in human antigen presenting cells

(2008) Claudia Skazik et al.   EXPERIMENTAL DERMATOLOGY

T-cell effector pathways in allergic diseases: Transcriptional mechanisms and therapeutic targets

(2008) Talal A. Chatila et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Toll-like receptor and IL-12 signaling control susceptibility to contact hypersensitivity

(2008) Stefan F. Martin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Depletion of Human Peripheral Blood Lymphocytes in CD25+ Cells Allows for the Sensitive In Vitro Screening of Contact Allergens

(2008) Marc Vocanson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Skin Exposure to Weak and Moderate Contact Allergens Induces IFNγ Production by Lymph Node Cells of CD4+ T-Cell-Depleted Mice

(2008) Marc Vocanson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IL-10-Producing Langerhans Cells and Regulatory T Cells Are Responsible for Depressed Contact Hypersensitivity in Grafted Skin

(2008) Ryutaro Yoshiki et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset

(2008) Marc Veldhoen et al.   NATURE IMMUNOLOGY

IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

(2008) Valérie Dardalhon et al.   NATURE IMMUNOLOGY

The Respiratory Local Lymph Node Assay as a Tool to Study Respiratory Sensitizers

(2008) Josje H. E. Arts et al.   TOXICOLOGICAL SCIENCES

HMOX1 and NQO1 Genes are Upregulated in Response to Contact Sensitizers in Dendritic Cells and THP-1 Cell Line: Role of the Keap1/Nrf2 Pathway

(2008) Nadège Ade et al.   TOXICOLOGICAL SCIENCES

Cytochrome P450-mediated activation of the fragrance compound geraniol forms potent contact allergens

(2008) Lina Hagvall et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A cell-based in vitro alternative to identify skin sensitizers by gene expression

(2008) Jef Hooyberghs et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Primer: inflammasomes and interleukin 1β in inflammatory disorders

(2008) Leigh D Church et al.   Nature clinical practice. Rheumatology

Allergic Contact Dermatitis––Formation, Structural Requirements, and Reactivity of Skin Sensitizers

(2007) Ann-Therese Karlberg et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Human Natural Killer T Cells Infiltrate into the Skin at Elicitation Sites of Allergic Contact Dermatitis

(2007) Michael D. Gober et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Dermal sensitization quantitative risk assessment (QRA) for fragrance ingredients

(2007) Anne Marie Api et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY