The impact of cyclin-dependent kinase 5 depletion on poly(ADP-ribose) polymerase activity and responses to radiation

Cdk5, the multifunctional surveyor

(2010) Vassiliki Lalioti et al.   CELL CYCLE

Poly (ADP-Ribose) Polymerase as a Novel Therapeutic Target in Cancer

(2010) C. M. Annunziata et al.   CLINICAL CANCER RESEARCH

The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death

(2010) En Huang et al.   NATURE CELL BIOLOGY

Radiation-induced mitotic catastrophe in PARG-deficient cells

(2009) J.-C. Ame et al.   JOURNAL OF CELL SCIENCE

Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death

(2009) Bo Tian et al.   NATURE CELL BIOLOGY

A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor

(2008) Nicholas C Turner et al.   EMBO JOURNAL

The role of poly(ADP-ribosyl)ation in epigenetic events

(2008) Delphine Quénet et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer

(2008) Thomas D. Penning et al.   JOURNAL OF MEDICINAL CHEMISTRY

Proteomic Investigation of Phosphorylation Sites in Poly(ADP-ribose) Polymerase-1 and Poly(ADP-ribose) Glycohydrolase

(2008) Jean-Philippe Gagné et al.   JOURNAL OF PROTEOME RESEARCH

PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility

(2008) C. Godon et al.   NUCLEIC ACIDS RESEARCH

Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

(2008) Jean-Philippe Gagné et al.   NUCLEIC ACIDS RESEARCH

Nuclear localization of Cdk5 is a key determinant in the postmitotic state of neurons

(2008) J. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA