Regulation and function of IL-17A- and IL-22-producing γδ T cells

Th17-Polarized Immune Response in a Murine Model of Hypersensitivity Pneumonitis and Lung Fibrosis

(2014) P. L. Simonian et al.   JOURNAL OF IMMUNOLOGY

SCART Scavenger Receptors Identify a Novel Subset of Adult    T Cells

(2014) J. Kisielow et al.   JOURNAL OF IMMUNOLOGY

Tyk2-Signaling Plays an Important Role in Host Defense against Escherichia coli through IL-23-Induced IL-17 Production by    T Cells

(2014) R. Nakamura et al.   JOURNAL OF IMMUNOLOGY

Identification of CD25+    T Cells As Fetal Thymus-Derived Naturally Occurring IL-17 Producers

(2014) K. Shibata et al.   JOURNAL OF IMMUNOLOGY

IL-17A Produced by    T Cells Plays a Critical Role in Innate Immunity against Listeria monocytogenes Infection in the Liver

(2014) S. Hamada et al.   JOURNAL OF IMMUNOLOGY

Th17 Cells, Not IL-17+    T Cells, Drive Arthritic Bone Destruction in Mice and Humans

(2011) B. Pollinger et al.   JOURNAL OF IMMUNOLOGY

Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of coxsackievirus b3-induced viral myocarditis reduces myocardium inflammation

(2011) Yang Fan et al.   Virology Journal

Microbial Colonization Drives Expansion of IL-1 Receptor 1-Expressing and IL-17-Producing γ/δ T Cells

(2010) Jinyou Duan et al.   Cell Host & Microbe

Interleukin 17-Producing γδ T Cells Increased in Patients with Active Pulmonary Tuberculosis

(2010) Meiyu Peng et al.   Cellular & Molecular Immunology

γδ T Cells Enhance Autoimmunity by Restraining Regulatory T Cell Responses via an Interleukin-23-Dependent Mechanism

(2010) Franziska Petermann et al.   IMMUNITY

The Candida Th17 response is dependent on mannan- and  -glucan-induced prostaglandin E2

(2010) S. P. Smeekens et al.   INTERNATIONAL IMMUNOLOGY

IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice

(2010) John S. Cho et al.   JOURNAL OF CLINICAL INVESTIGATION

γδ T cells protect against lung fibrosis via IL-22

(2010) Philip L. Simonian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human cytomegalovirus elicits fetal γδ T cell responses in utero

(2010) David Vermijlen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human Th17 Cells Comprise Heterogeneous Subsets Including IFN- -Producing Cells with Distinct Properties from the Th1 Lineage

(2010) K. Boniface et al.   JOURNAL OF IMMUNOLOGY

IL-17A-Producing    T and Th17 Lymphocytes Mediate Lung Inflammation but Not Fibrosis in Experimental Silicosis

(2010) S. Lo Re et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Spontaneous Development of IL-17–Producing γδ T Cells in the Thymus Occurs via a TGF-β1–Dependent Mechanism

(2010) Jeong-su Do et al.   JOURNAL OF IMMUNOLOGY

IL-23 Receptor Regulates Unconventional IL-17–Producing T Cells That Control Bacterial Infections

(2010) Lorena Riol-Blanco et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Adaptive Versus Innate Receptor Signals Selectively Control the Pool Sizes of Murine IFN- - or IL-17-Producing    T Cells upon Infection

(2010) J. C. Ribot et al.   JOURNAL OF IMMUNOLOGY

V 2V 2 T Cell Receptor Recognition of Prenyl Pyrophosphates Is Dependent on All CDRs

(2010) H. Wang et al.   JOURNAL OF IMMUNOLOGY

Cytokine Requirements for the Differentiation and Expansion of IL-17A- and IL-22-Producing Human V 2V 2 T Cells

(2010) K. J. Ness-Schwickerath et al.   JOURNAL OF IMMUNOLOGY

IL-17 Promotes p38 MAPK-Dependent Endothelial Activation Enhancing Neutrophil Recruitment to Sites of Inflammation

(2010) L. Roussel et al.   JOURNAL OF IMMUNOLOGY

Essential Role of IL-17A in the Formation of a Mycobacterial Infection-Induced Granuloma in the Lung

(2010) Y. Okamoto Yoshida et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis induces IL-17A responses through TLR4 and dectin-1 and is critically dependent on endogenous IL-1

(2010) F. L. van de Veerdonk et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

(2010) Lionel Apetoh et al.   NATURE IMMUNOLOGY

Differentiation, Distribution and γδ T Cell-Driven Regulation of IL-22-Producing T Cells in Tuberculosis

(2010) Shuyu Yao et al.   PLoS Pathogens

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis

(2009) Yoshinaga Ito et al.   ARTHRITIS AND RHEUMATISM

Human γδ T cell Recognition of lipid A is predominately presented by CD1b or CD1c on dendritic cells

(2009) Yongchun Cui et al.   Biology Direct

V 1 T lymphocytes producing IFN-  and IL-17 are expanded in HIV-1-infected patients and respond to Candida albicans

(2009) D. Fenoglio et al.   BLOOD

CCR6 and NK1.1 distinguish between IL-17A and IFN-γ-producing γδ effector T cells

(2009) Jan D. Haas et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

γδ T cells in EAE: Early trafficking events and cytokine requirements

(2009) Jillian E. Wohler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Prostaglandin E2 enhances Th17 responses via modulation of IL-17 and IFN-γ production by memory CD4+ T cells

(2009) Giorgio Napolitani et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TGF-β indirectly favors the development of human Th17 cells by inhibiting Th1 cells

(2009) Veronica Santarlasci et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Neonates harbour highly active γδ T cells with selective impairments in preterm infants

(2009) Deena L. Gibbons et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cellular mechanisms of IL-17-induced blood-brain barrier disruption

(2009) Jula Huppert et al.   FASEB JOURNAL

Plasticity of CD4+ T Cell Lineage Differentiation

(2009) Liang Zhou et al.   IMMUNITY

Interleukin-17-Producing γδ T Cells Selectively Expand in Response to Pathogen Products and Environmental Signals

(2009) Bruno Martin et al.   IMMUNITY

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

(2009) Caroline E. Sutton et al.   IMMUNITY

Transforming growth factor β is dispensable for the molecular orchestration of Th17 cell differentiation

(2009) Jyoti Das et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling

(2009) Katia Boniface et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-17A-Expressing T Cells Are Essential for Bacterial Clearance in a Murine Model of Hypersensitivity Pneumonitis

(2009) Philip L. Simonian et al.   JOURNAL OF IMMUNOLOGY

IRAK4 Kinase Activity Is Required for Th17 Differentiation and Th17-Mediated Disease

(2009) K. A. Staschke et al.   JOURNAL OF IMMUNOLOGY

Tc17 CD8 T Cells: Functional Plasticity and Subset Diversity

(2009) H.-R. Yen et al.   JOURNAL OF IMMUNOLOGY

Regulation of Airway MUC5AC Expression by IL-1  and IL-17A; the NF- B Paradigm

(2009) T. Fujisawa et al.   JOURNAL OF IMMUNOLOGY

IL-23 Is Required for Protection against Systemic Infection with Listeria monocytogenes

(2009) K. D. Meeks et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Phenotypic Characterization and Differentiation of Human CD8+ T Cells Producing IL-17

(2009) T. Kondo et al.   JOURNAL OF IMMUNOLOGY

Neonatal Innate TLR-Mediated Responses Are Distinct from Those of Adults

(2009) T. R. Kollmann et al.   JOURNAL OF IMMUNOLOGY

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo

(2009) Mandy J McGeachy et al.   NATURE IMMUNOLOGY

CD27 is a thymic determinant of the balance between interferon-γ- and interleukin 17–producing γδ T cell subsets

(2009) Julie C Ribot et al.   NATURE IMMUNOLOGY

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

(2009) Thomas Duhen et al.   NATURE IMMUNOLOGY

Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury

(2009) Takashi Shichita et al.   NATURE MEDICINE

Interleukin-23 is critical for full-blown expression of a non-autoimmune destructive arthritis and regulates interleukin-17A and RORγt in γδ T cells

(2009) Ferry Cornelissen et al.   ARTHRITIS RESEARCH & THERAPY

Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-α, Oncostatin M and response to biologic therapies

(2009) Ellen M Moran et al.   ARTHRITIS RESEARCH & THERAPY

Long-term expansion of effector/memory V 2-    T cells is a specific blood signature of CMV infection

(2008) V. Pitard et al.   BLOOD

Structure–function relationships in the IL-17 receptor: Implications for signal transduction and therapy

(2008) Fang Shen et al.   CYTOKINE

Adverse functions of IL-17A in experimental sepsis

(2008) Michael A. Flierl et al.   FASEB JOURNAL

Thymic Selection Determines γδ T Cell Effector Fate: Antigen-Naive Cells Make Interleukin-17 and Antigen-Experienced Cells Make Interferon γ

(2008) Kirk D.C. Jensen et al.   IMMUNITY

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

(2008) Xuexian O. Yang et al.   IMMUNITY

Endogenous Naive CD8+ T Cell Precursor Frequency Regulates Primary and Memory Responses to Infection

(2008) Joshua J. Obar et al.   IMMUNITY

Importance of murine Vδ1+γδ T cells expressing interferon-γ and interleukin-17A in innate protection againstListeria monocytogenesinfection

(2008) Satoru Hamada et al.   IMMUNOLOGY

IL-17 Producing γδ T Cells are Required for a Controlled Inflammatory Response after Bleomycin-induced Lung Injury

(2008) Ruedi K. Braun et al.   INFLAMMATION

The Serine Protease Marapsin Is Expressed in Stratified Squamous Epithelia and Is Up-regulated in the Hyperproliferative Epidermis of Psoriasis and Regenerating Wounds

(2008) Wei Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

(2008) Marc Veldhoen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

In vivo equilibrium of proinflammatory IL-17+and regulatory IL-10+Foxp3+RORγt+T cells

(2008) Matthias Lochner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Macrophages express multiple ligands for γδ TCRs

(2008) M. Kemal Aydintug et al.   MOLECULAR IMMUNOLOGY

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

(2008) Marc Veldhoen et al.   NATURE

IL-21 and TGF-β are required for differentiation of human TH17 cells

(2008) Li Yang et al.   NATURE

Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17–producing T cells

(2008) Fuping Zhang et al.   NATURE IMMUNOLOGY

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

(2008) Elisabetta Volpe et al.   NATURE IMMUNOLOGY

The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt

(2008) Nicolas Manel et al.   NATURE IMMUNOLOGY

IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype

(2008) M. Huber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells

(2008) A. Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor

(2007) Linh P. Nguyen et al.   CHEMICAL RESEARCH IN TOXICOLOGY