The role of endocytosis in activating and regulating signal transduction

Caveolin-1 Regulates γ-Secretase-Mediated AβPP Processing by Modulating Spatial Distribution of γ-Secretase in Membrane

(2017) Arun Kapoor et al.   JOURNAL OF ALZHEIMERS DISEASE

The ciliary pocket: a once-forgotten membrane domain at the base of cilia

(2011) Rania Ghossoub et al.   BIOLOGY OF THE CELL

Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes

(2011) Sarah Affentranger et al.   BMC CELL BIOLOGY

A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development

(2011) Ellen J. Ezratty et al.   CELL

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

(2011) Bence György et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanism and Significance of cis-Inhibition in Notch Signalling

(2011) David del Álamo et al.   CURRENT BIOLOGY

Notch signaling: simplicity in design, versatility in function

(2011) E. R. Andersson et al.   DEVELOPMENT

Noncanonical notch function in motor axon guidance is mediated by Rac GTPase and the GEF1 domain of trio

(2011) Jeong K. Song et al.   DEVELOPMENTAL DYNAMICS

Roles of Drosophila Deltex in Notch receptor endocytic trafficking and activation

(2011) Kenta Yamada et al.   GENES TO CELLS

SH3YL1 regulates dorsal ruffle formation by a novel phosphoinositide-binding domain

(2011) Junya Hasegawa et al.   JOURNAL OF CELL BIOLOGY

Endocytic adaptors - social networking at the plasma membrane

(2011) A. Reider et al.   JOURNAL OF CELL SCIENCE

RhoB links PDGF signaling to cell migration by coordinating activation and localization of Cdc42 and Rac

(2011) Minzhou Huang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Numb regulates Notch1, but not Notch3, during myogenesis

(2011) Brian J. Beres et al.   MECHANISMS OF DEVELOPMENT

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

(2011) M Laura Cremona et al.   NATURE NEUROSCIENCE

Propagating Cell-Membrane Waves Driven by Curved Activators of Actin Polymerization

(2011) Barak Peleg et al.   PLoS One

Critical roles for EphB and ephrin-B bidirectional signalling in retinocollicular mapping

(2011) Sonal Thakar et al.   Nature Communications

Ectodomain shedding of the Notch ligand Jagged1 is mediated by ADAM17, but is not a lipid-raft-associated event

(2010) Catherine A. Parr-Sturgess et al.   BIOCHEMICAL JOURNAL

Microdomain-forming proteins and the role of the reggies/flotillins during axon regeneration in zebrafish

(2010) Claudia A.O. Stuermer   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Differential involvement of caveolin-1 in brown adipocyte signaling: Impaired β3-adrenergic, but unaffected LPA, PDGF and EGF receptor signaling

(2010) Charlotte L. Mattsson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes

(2010) H. Sheldon et al.   BLOOD

An Updated Overview on Wnt Signaling Pathways

(2010) Tata Purushothama Rao et al.   CIRCULATION RESEARCH

Endocytic Internalization Routes Required for Delta/Notch Signaling

(2010) Sarah L. Windler et al.   CURRENT BIOLOGY

Eph/ephrin molecules--a hub for signaling and endocytosis

(2010) M. E. Pitulescu et al.   GENES & DEVELOPMENT

Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism

(2010) Nao Hiramoto-Yamaki et al.   JOURNAL OF CELL BIOLOGY

The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia

(2010) A. Molla-Herman et al.   JOURNAL OF CELL SCIENCE

Control of Notch-ligand endocytosis by ligand-receptor interaction

(2010) E. M. Hansson et al.   JOURNAL OF CELL SCIENCE

Mechanisms of cellular communication through intercellular protein transfer

(2010) Khawaja Ashfaque Ahmed et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Intoxication of zebrafish and mammalian cells by cholera toxin depends on the flotillin/reggie proteins but not Derlin-1 or -2

(2010) David E. Saslowsky et al.   JOURNAL OF CLINICAL INVESTIGATION

EphA4 is localized in clathrin-coated and synaptic vesicles in adult mouse brain

(2010) David Bouvier et al.   JOURNAL OF NEUROCHEMISTRY

The kinesin KIF9 and reggie/flotillin proteins regulate matrix degradation by macrophage podosomes

(2010) Susanne Cornfine et al.   MOLECULAR BIOLOGY OF THE CELL

EphA8-ephrinA5 signaling and clathrin-mediated endocytosis is regulated by Tiam-1, a Rac-specific guanine nucleotide exchange factor

(2010) Sooyeon Yoo et al.   MOLECULES AND CELLS

Dkk1 Stabilizes Wnt Co-Receptor LRP6: Implication for Wnt Ligand-Induced LRP6 Down-Regulation

(2010) Yonghe Li et al.   PLoS One

A Septin Diffusion Barrier at the Base of the Primary Cilium Maintains Ciliary Membrane Protein Distribution

(2010) Q. Hu et al.   SCIENCE

γ-Secretase-Dependent Cleavage Initiates Notch Signaling from the Plasma Membrane

(2010) Erika B. Sorensen et al.   TRAFFIC

The Translation Initiation Factor 3f (eIF3f) Exhibits a Deubiquitinase Activity Regulating Notch Activation

(2010) Julien Moretti et al.   PLOS BIOLOGY

Mechanisms of Endocytosis

(2009) Gary J. Doherty et al.   Annual Review of Biochemistry

Hetero-oligomerization of reggie-1/flotillin-2 and reggie-2/flotillin-1 is required for their endocytosis

(2009) Tanja Babuke et al.   CELLULAR SIGNALLING

Dishevelled: The hub of Wnt signaling

(2009) Chan Gao et al.   CELLULAR SIGNALLING

Towards an integrated view of Wnt signaling in development

(2009) R. van Amerongen et al.   DEVELOPMENT

Wnt5a regulates distinct signalling pathways by binding to Frizzled2

(2009) Akira Sato et al.   EMBO JOURNAL

SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function

(2009) Kerrie-Ann McMahon et al.   EMBO JOURNAL

Wnt signaling pathways meet Rho GTPases

(2009) K. Schlessinger et al.   GENES & DEVELOPMENT

Numb Regulates Post-endocytic Trafficking and Degradation of Notch1

(2009) Melanie A. McGill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptic activity prompts γ-secretase–mediated cleavage of EphA4 and dendritic spine formation

(2009) Eiji Inoue et al.   JOURNAL OF CELL BIOLOGY

The Use of Inhibitors to Study Endocytic Pathways of Gene Carriers: Optimization and Pitfalls

(2009) Dries Vercauteren et al.   MOLECULAR THERAPY

The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors

(2009) Akhila Rajan et al.   NATURE CELL BIOLOGY

SDPR induces membrane curvature and functions in the formation of caveolae

(2009) Carsten G. Hansen et al.   NATURE CELL BIOLOGY

The trypanosome flagellar pocket

(2009) Mark C. Field et al.   NATURE REVIEWS MICROBIOLOGY

Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice

(2009) H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway

(2009) Isabelle Roszko et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cytoplasmic Relaxation of Active Eph Controls Ephrin Shedding by ADAM10

(2009) Peter W. Janes et al.   PLOS BIOLOGY

PTRF-Cavin, a Conserved Cytoplasmic Protein Required for Caveola Formation and Function

(2008) Michelle M. Hill et al.   CELL

Eph-Ephrin Bidirectional Signaling in Physiology and Disease

(2008) Elena B. Pasquale   CELL

ADAM proteases: ligand processing and modulation of the Notch pathway

(2008) A. Zolkiewska   CELLULAR AND MOLECULAR LIFE SCIENCES

Drosophila HOPS and AP-3 Complex Genes Are Required for a Deltex-Regulated Activation of Notch in the Endosomal Trafficking Pathway

(2008) Marian Wilkin et al.   DEVELOPMENTAL CELL

Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila

(2008) Vladimir L Katanaev et al.   EMBO JOURNAL

Intramembrane Proteolysis by γ-Secretase

(2008) Harald Steiner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct and Potent Regulation of γ-Secretase by Its Lipid Microenvironment

(2008) Pamela Osenkowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endosomal entry regulates Notch receptor activation inDrosophila melanogaster

(2008) Thomas Vaccari et al.   JOURNAL OF CELL BIOLOGY

Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential forXenopus laevisconvergent extension movements

(2008) Gun-Hwa Kim et al.   JOURNAL OF CELL BIOLOGY

Trans-endocytosis of CD47 and SHPS-1 and its role in regulation of the CD47-SHPS-1 system

(2008) S. Kusakari et al.   JOURNAL OF CELL SCIENCE

Evolutionary analysis and molecular dissection of caveola biogenesis

(2008) M. Kirkham et al.   JOURNAL OF CELL SCIENCE

Flotillin-Dependent Clustering of the Amyloid Precursor Protein Regulates Its Endocytosis and Amyloidogenic Processing in Neurons

(2008) A. Schneider et al.   JOURNAL OF NEUROSCIENCE

Mechanisms of asymmetric cell division: flies and worms pave the way

(2008) Pierre Gönczy   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Wnt5a Regulates Ventral Midbrain Morphogenesis and the Development of A9–A10 Dopaminergic Cells In Vivo

(2008) Emma R. Andersson et al.   PLoS One

The intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity

(2008) S. F. Heuss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Rab5 guanylate exchange factor Rin1 regulates endocytosis of the EphA4 receptor in mature excitatory neurons

(2008) K. Deininger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA