Role of xenobiotic metabolism in cancer: involvement of transcriptional and miRNA regulation of P450s

The Transcriptional Regulation of the Human CYP2C Genes

(2012) Yuping Chen et al.   CURRENT DRUG METABOLISM

When NRF2 Talks, Who's Listening?

(2010) Nobunao Wakabayashi et al.   ANTIOXIDANTS & REDOX SIGNALING

The aryl hydrocarbon receptor (AhR) in the regulation of cell-cell contact and tumor growth

(2010) C. Dietrich et al.   CARCINOGENESIS

Cytochrome P450 2A5 Constitutive Expression and Induction by Heavy Metals Is Dependent on Redox-Sensitive Transcription Factor Nrf2 in Liver

(2010) Virpi Lämsä et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Efficient Hypoxic Activation of the Anticancer Agent AQ4N by CYP2S1 and CYP2W1

(2010) C. R. Nishida et al.   MOLECULAR PHARMACOLOGY

Up-Regulation of Human CYP2J2 in HepG2 Cells by Butylated Hydroxyanisole Is Mediated by c-Jun and Nrf2

(2010) A. C. Lee et al.   MOLECULAR PHARMACOLOGY

Human CYP2E1 is regulated by miR-378

(2009) Takuya Mohri et al.   BIOCHEMICAL PHARMACOLOGY

Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention

(2009) Vasilis P Androutsopoulos et al.   BMC CANCER

Clinical pharmacokinetics of tyrosine kinase inhibitors

(2009) Nielka P. van Erp et al.   CANCER TREATMENT REVIEWS

Hormonal regulation of CYP1A expression

(2009) Katalin Monostory et al.   DRUG METABOLISM REVIEWS

Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment

(2009) Cristina Rodriguez-Antona et al.   HUMAN GENETICS

CYP1B1, but not CYP1A1, is downregulated by promoter methylation in colorectal cancers

(2009) Habano   INTERNATIONAL JOURNAL OF ONCOLOGY

Epigenetic Regulation of Transcriptional Activity of Pregnane X Receptor by Protein Arginine Methyltransferase 1

(2009) Ying Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular modeling of human cytochrome P450 2W1 and its interactions with substrates

(2009) Weihua Li et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Genetic Predictors of Interindividual Variability in Hepatic CYP3A4 Expression

(2009) V. Lamba et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Cross-talk between Transcription Factors AhR and Nrf2: Lessons for Cancer Chemoprevention from Dioxin

(2009) John D. Hayes et al.   TOXICOLOGICAL SCIENCES

Crosstalk between activated forms of the aryl hydrocarbon receptor and glucocorticoid receptor

(2009) Shao-Hung Wang et al.   TOXICOLOGY

NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

(2009) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways

(2008) Alvaro Puga et al.   BIOCHEMICAL PHARMACOLOGY

Differential expression of microRNAs in early-stage neoplastic transformation in the lungs of F344 rats chronically treated with the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

(2008) Stephen Kalscheuer et al.   CARCINOGENESIS

The aryl hydrocarbon receptor (AhR) inhibits vanadate-induced vascular endothelial growth factor (VEGF) production in TRAMP prostates

(2008) Wayne A. Fritz et al.   CARCINOGENESIS

Xenobiotic-Activated Receptors: From Transcription to Drug Metabolism to Disease

(2008) Qiang Ma   CHEMICAL RESEARCH IN TOXICOLOGY

Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes

(2008) Radim Vrzal et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Interplay of Pregnane X receptor with Other Nuclear Receptors on Gene Regulation

(2008) Yun-Ping Lim et al.   Drug Metabolism and Pharmacokinetics

The expression of the novel CYP2W1 enzyme is an independent prognostic factor in colorectal cancer – A pilot study

(2008) David Edler et al.   EUROPEAN JOURNAL OF CANCER

Post-transcriptional Regulation of Human Pregnane X Receptor by Micro-RNA Affects the Expression of Cytochrome P450 3A4

(2008) Shingo Takagi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Changes in miRNA expression in solid tumors: An miRNA profiling in melanomas

(2008) Viktor Molnár et al.   SEMINARS IN CANCER BIOLOGY

The Tangle of Nuclear Receptors that Controls Xenobiotic Metabolism and Transport: Crosstalk and Consequences

(2007) Jean-Marc Pascussi et al.   Annual Review of Pharmacology and Toxicology

The far and distal enhancers in theCYP3A4gene co-ordinate the proximal promoter in responding similarly to the pregnane X receptor but differentially to hepatocyte nuclear factor-4α

(2007) Fu-Jun Liu et al.   BIOCHEMICAL JOURNAL