Nuclear Stiffening Inhibits Migration of Invasive Melanoma Cells

On the role of the actin cytoskeleton and nucleus in the biomechanical response of spread cells

(2014) Noel H. Reynolds et al.   BIOMATERIALS

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

(2014) Takamasa Harada et al.   JOURNAL OF CELL BIOLOGY

Identification of differential protein interactors of lamin A and progerin

(2014) Nard Kubben et al.   Nucleus

Calcium Causes a Conformational Change in Lamin A Tail Domain that Promotes Farnesyl-Mediated Membrane Association

(2013) Agnieszka Kalinowski et al.   BIOPHYSICAL JOURNAL

Hutchinson–Gilford progeria syndrome alters nuclear shape and reduces cell motility in three dimensional model substrates

(2013) Elizabeth A. Booth-Gauthier et al.   Integrative Biology

CD82/KAI expression prevents IL-8-mediated endothelial gap formation in late-stage melanomas

(2013) P Khanna et al.   ONCOGENE

Intracellular Mechanics and Activity of Breast Cancer Cells Correlate with Metastatic Potential

(2012) Naama Gal et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Tumor cell migration in complex microenvironments

(2012) William J. Polacheck et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanical characterization of adult stem cells from bone marrow and perivascular niches

(2012) Alexandre J.S. Ribeiro et al.   JOURNAL OF BIOMECHANICS

Investigation of nuclear nano-morphology marker as a biomarker for cancer risk assessment using a mouse model

(2012) Rajan K. Bista   JOURNAL OF BIOMEDICAL OPTICS

Higher cell stiffness indicating lower metastatic potential in B16 melanoma cell variants and in (−)-epigallocatechin gallate-treated cells

(2012) Tatsuro Watanabe et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

DNA damage checkpoints in stem cells, ageing and cancer

(2012) Tobias Sperka et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Independent regulation of tumor cell migration by matrix stiffness and confinement

(2012) A. Pathak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear lamin functions and disease

(2012) Veronika Butin-Israeli et al.   TRENDS IN GENETICS

Mechanical Stiffness Grades Metastatic Potential in Patient Tumor Cells and in Cancer Cell Lines

(2011) V. Swaminathan et al.   CANCER RESEARCH

Older Age Predicts Decreased Metastasis and Prostate Cancer-Specific Death for Men Treated With Radiation Therapy: Meta-Analysis of Radiation Therapy Oncology Group Trials

(2011) Daniel A. Hamstra et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Structure and stability of the lamin A tail domain and HGPS mutant

(2011) Zhao Qin et al.   JOURNAL OF STRUCTURAL BIOLOGY

Epithelial organization, cell polarity and tumorigenesis

(2011) Luke Martin McCaffrey et al.   TRENDS IN CELL BIOLOGY

Mesenchymal Stem Cell Mechanics from the Attached to the Suspended State

(2010) John M. Maloney et al.   BIOPHYSICAL JOURNAL

Transiently Entrapped Circulating Tumor Cells Interact with Neutrophils to Facilitate Lung Metastasis Development

(2010) S. J. Huh et al.   CANCER RESEARCH

Nuclear mechanics during cell migration

(2010) Peter Friedl et al.   CURRENT OPINION IN CELL BIOLOGY

Disruption of IGF-1R signaling increases TRAIL-induced apoptosis: A new potential therapy for the treatment of melanoma

(2010) Thomas B. Karasic et al.   EXPERIMENTAL CELL RESEARCH

Sequential Binding of  v 3 and ICAM-1 Determines Fibrin-Mediated Melanoma Capture and Stable Adhesion to CD11b/CD18 on Neutrophils

(2010) P. Zhang et al.   JOURNAL OF IMMUNOLOGY

Diseases of the Nuclear Envelope

(2010) H. J. Worman et al.   Cold Spring Harbor Perspectives in Biology

Cell Mechanics: Dissecting the Physical Responses of Cells to Force

(2009) Brenton D. Hoffman et al.   Annual Review of Biomedical Engineering

Mechanics, malignancy, and metastasis: The force journey of a tumor cell

(2009) Sanjay Kumar et al.   CANCER AND METASTASIS REVIEWS

Reduced expression of lamin A/C correlates with poor histological differentiation and prognosis in primary gastric carcinoma

(2009) Zhengrong Wu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Hydrodynamic Shear Rate Regulates Melanoma-Leukocyte Aggregation, Melanoma Adhesion to the Endothelium, and Subsequent Extravasation

(2008) Shile Liang et al.   ANNALS OF BIOMEDICAL ENGINEERING

Deformability study of breast cancer cells using microfluidics

(2008) H. W. Hou et al.   BIOMEDICAL MICRODEVICES

Nuclear mechanotransduction: Response of the lamina to extracellular stress with implications in aging

(2008) Julia T. Philip et al.   JOURNAL OF BIOMECHANICS