Amino acids 89–96 of Salmonella typhimurium flagellin represent the major domain responsible for TLR5-independent adjuvanticity in the humoral immune response

Deletion of Flagellin's Hypervariable Region Abrogates Antibody-Mediated Neutralization and Systemic Activation of TLR5-Dependent Immunity

(2014) C. Nempont et al.   JOURNAL OF IMMUNOLOGY

Flagellin Induces Antibody Responses through a TLR5- and Inflammasome-Independent Pathway

(2014) A. H. Lopez-Yglesias et al.   JOURNAL OF IMMUNOLOGY

Toll-like receptor 5 (TLR5), IL-1  secretion, and asparagine endopeptidase are critical factors for alveolar macrophage phagocytosis and bacterial killing

(2012) D. Descamps et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of TLR5-Flagellin Recognition and Signaling

(2012) S.-i. Yoon et al.   SCIENCE

Development of VAX128, a recombinant hemagglutinin (HA) influenza-flagellin fusion vaccine with improved safety and immune response

(2012) David N. Taylor et al.   VACCINE

Chimeric flagellin expressed by Salmonella typhimurium induces an ESAT-6-specific Th1-type immune response and CTL effects following intranasal immunization

(2011) Hui Zhang et al.   Cellular & Molecular Immunology

TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin

(2010) Matam Vijay-Kumar et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Flagellin as an Adjuvant: Cellular Mechanisms and Potential

(2010) S. B. Mizel et al.   JOURNAL OF IMMUNOLOGY

TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage

(2010) F A Carvalho et al.   Mucosal Immunology

Protein refolding is required for assembly of the type three secretion needle

(2010) Ömer Poyraz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

(2010) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of adaptive immunity by flagellin does not require robust activation of innate immunity

(2009) Catherine J. Sanders et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inflammasomes: guardians of cytosolic sanctity

(2008) Mohamed Lamkanfi et al.   IMMUNOLOGICAL REVIEWS

Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

(2008) Karla L Lightfield et al.   NATURE IMMUNOLOGY