γδ-T cells: an unpolished sword in human anti-infection immunity

Characterization of the Immune Response of Human Cord-Blood Derived γδ T Cells to Stimulation with Aminobisphosphonate Compounds

(2017) R. Placido et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Definition of APC Presentation of Phosphoantigen (E)-4-Hydroxy-3-methyl-but-2-enyl Pyrophosphate to V 2V 2 TCR

(2014) H. Wei et al.   JOURNAL OF IMMUNOLOGY

Photoaffinity Antigens for Human    T Cells

(2014) G. Sarikonda et al.   JOURNAL OF IMMUNOLOGY

Homeostatic maintenance of T cells and natural killer cells

(2012) Onur Boyman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Target Specificity of an Autoreactive Pathogenic Human γδ-T Cell Receptor in Myositis

(2012) Jessica Bruder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammasome-Derived IL-1  Regulates the Production of GM-CSF by CD4+ T Cells and    T Cells

(2012) J. R. Lukens et al.   JOURNAL OF IMMUNOLOGY

Role of    T Cells in  -Galactosylceramide-Mediated Immunity

(2012) C. Paget et al.   JOURNAL OF IMMUNOLOGY

Phenotypic and Functional Characterization of Human γδ T-Cell Subsets in Response to Influenza A Viruses

(2012) Gang Qin et al.   JOURNAL OF INFECTIOUS DISEASES

Antibody-dependent anti-cytomegalovirus activity of human    T cells expressing CD16 (Fc RIIIa)

(2011) L. Couzi et al.   BLOOD

DC-like cell-dependent activation of human natural killer cells by the bisphosphonate zoledronic acid is regulated by    T lymphocytes

(2011) O. Nussbaumer et al.   BLOOD

Bisphosphonates: The first 40years

(2011) R. Graham G. Russell   BONE

Activated human γδ T cells induce peptide-specific CD8+ T-cell responses to tumor-associated self-antigens

(2011) Bianca Altvater et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Anti-γδ TCR antibody-expanded γδ T cells: a better choice for the adoptive immunotherapy of lymphoid malignancies

(2011) Jianhua Zhou et al.   Cellular & Molecular Immunology

Immune biology of Ag-specific γδ T cells in infections

(2011) Zheng W. Chen   CELLULAR AND MOLECULAR LIFE SCIENCES

γδ T-APCs: a novel tool for immunotherapy?

(2011) Bernhard Moser et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

γδ T-cells: cross-talk between innate and adaptive immunity

(2011) Dieter Kabelitz   CELLULAR AND MOLECULAR LIFE SCIENCES

Dynamics of the interaction of γδ T cells with their neighbors in vivo

(2011) Immo Prinz   CELLULAR AND MOLECULAR LIFE SCIENCES

Modulation of γδ T cell responses by TLR ligands

(2011) Daniela Wesch et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Searching for “signal 2”: costimulation requirements of γδ T cells

(2011) Julie C. Ribot et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Peptide antigens for gamma/delta T cells

(2011) Willi K. Born et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Caspase-1-processed IL-1 family cytokines play a vital role in driving innate IL-17

(2011) Lara S. Dungan et al.   CYTOKINE

CD4+Foxp3+ regulatory T cells suppress γδ T-cell effector functions in a model of T-cell-induced mucosal inflammation

(2011) Ekaterina Yurchenko et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CCL20, γδ T cells, and IL-22 in corneal epithelial healing

(2011) Zhijie Li et al.   FASEB JOURNAL

Recent advances in IL-22 biology

(2011) L. A. Zenewicz et al.   INTERNATIONAL IMMUNOLOGY

The aminobisphosphonate pamidronate controls influenza pathogenesis by expanding a γδ T cell population in humanized mice

(2011) Wenwei Tu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immune Modulation by Zoledronic Acid in Human Myeloma: An Advantageous Cross-Talk between V 9V 2 T Cells,    CD8+ T Cells, Regulatory T Cells, and Dendritic Cells

(2011) B. Castella et al.   JOURNAL OF IMMUNOLOGY

Role for E-Cadherin as an Inhibitory Receptor on Epidermal    T Cells

(2011) Y. Uchida et al.   JOURNAL OF IMMUNOLOGY

Cardiolipin Binds to CD1d and Stimulates CD1d-Restricted    T Cells in the Normal Murine Repertoire

(2011) M. Dieude et al.   JOURNAL OF IMMUNOLOGY

Caspase-1-Processed Cytokines IL-1  and IL-18 Promote IL-17 Production by    and CD4 T Cells That Mediate Autoimmunity

(2011) S. J. Lalor et al.   JOURNAL OF IMMUNOLOGY

Generation of Human Regulatory    T Cells by TCR   Stimulation in the Presence of TGF-  and Their Involvement in the Pathogenesis of Systemic Lupus Erythematosus

(2011) X. Li et al.   JOURNAL OF IMMUNOLOGY

Mechanisms controlling Th17 cytokine expression and host defense

(2011) Jeremy P. McAleer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

  T cells in Juvenile Idiopathic Arthritis: Higher Percentages of Synovial V 1+ and V 9+ T Cell Subsets Are Associated with Milder Disease

(2011) Y. BERKUN et al.   JOURNAL OF RHEUMATOLOGY

Type 1 Responses of Human V 9V 2 T Cells to Influenza A Viruses

(2011) G. Qin et al.   JOURNAL OF VIROLOGY

HMGB1 and Cord Blood: Its Role as Immuno-Adjuvant Factor in Innate Immunity

(2011) Alessandra Ciucci et al.   PLoS One

Molecular aspects of epithelial γδ T cell regulation

(2011) Deborah A. Witherden et al.   TRENDS IN IMMUNOLOGY

Cross-talk between cd1d-restricted nkt cells and gammadelta cells in t regulatory cell response

(2011) Wei Liu et al.   Virology Journal

Resolution of Allergic Airway Inflammation and Airway Hyperreactivity Is Mediated by IL-17–producing γδT Cells

(2010) Jenna R. Murdoch et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The role of V 2-negative    T cells during cytomegalovirus reactivation in recipients of allogeneic stem cell transplantation

(2010) A. Knight et al.   BLOOD

Human    T lymphocytes induce robust NK cell-mediated antitumor cytotoxicity through CD137 engagement

(2010) A. Maniar et al.   BLOOD

Blockade of Interleukin-17A Results in Reduced Atherosclerosis in Apolipoprotein E–Deficient Mice

(2010) Emily Smith et al.   CIRCULATION

A phase I study of adoptive immunotherapy for recurrent non-small-cell lung cancer patients with autologous γδ T cells☆☆☆

(2010) Jun Nakajima et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

γδd T cells promote the maturation of dendritic cells during West Nile virus infection

(2010) Hao Fang et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

A multifaceted imbalance of T cells with regulatory function characterizes type 1 autoimmune hepatitis

(2010) Silvia Ferri et al.   HEPATOLOGY

T Regulatory Cells Maintain Intestinal Homeostasis by Suppressing γδ T Cells

(2010) Sung-Gyoo Park et al.   IMMUNITY

γδ T lymphocytes kill T regulatory cells through CD1d

(2010) Sally A. Huber   IMMUNOLOGY

   T Cells but Not NK Cells Are Essential for Cell-Mediated Immunity against Plasmodium chabaudi Malaria

(2010) W. P. Weidanz et al.   INFECTION AND IMMUNITY

IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice

(2010) John S. Cho et al.   JOURNAL OF CLINICAL INVESTIGATION

Human cytomegalovirus elicits fetal γδ T cell responses in utero

(2010) David Vermijlen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Herpes Simplex Virus Infects Skin    T Cells before Langerhans Cells and Impedes Migration of Infected Langerhans Cells by Inducing Apoptosis and Blocking E-Cadherin Downregulation

(2010) F. K. Puttur et al.   JOURNAL OF IMMUNOLOGY

Differential but Direct Abolishment of Human Regulatory T Cell Suppressive Capacity by Various TLR2 Ligands

(2010) H. H. Oberg et al.   JOURNAL OF IMMUNOLOGY

Partial and Ineffective Activation of V 9V 2 T Cells by Mycobacterium tuberculosis-Infected Dendritic Cells

(2010) S. Meraviglia et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Intrinsic Programming of Thymic   T Cells for Specific Peripheral Tissue Localization

(2010) Y. Jin et al.   JOURNAL OF IMMUNOLOGY

Cross-Talk between T Cells and NK Cells Generates Rapid Effector Responses to Plasmodium falciparum-Infected Erythrocytes

(2010) A. Horowitz et al.   JOURNAL OF IMMUNOLOGY

Intra- and Intercompartmental Movement of    T Cells: Intestinal Intraepithelial and Peripheral    T Cells Represent Exclusive Nonoverlapping Populations with Distinct Migration Characteristics

(2010) V. Chennupati et al.   JOURNAL OF IMMUNOLOGY

IL-17A-Producing   T Cells Promote CTL Responses against Listeria monocytogenes Infection by Enhancing Dendritic Cell Cross-Presentation

(2010) S. Xu et al.   JOURNAL OF IMMUNOLOGY

Type I IFN Signaling Constrains IL-17A/F Secretion by    T Cells during Bacterial Infections

(2010) T. Henry et al.   JOURNAL OF IMMUNOLOGY

Bromohydrin Pyrophosphate-stimulated Vγ9δ2 T Cells Expanded Ex Vivo From Patients With Poor-Prognosis Neuroblastoma Lyse Autologous Primary Tumor Cells

(2010) Jamel Chargui et al.   JOURNAL OF IMMUNOTHERAPY

NKG2A inhibits NKG2C effector functions of γδ T cells: implications in health and disease

(2010) Daniela F. Angelini et al.   JOURNAL OF LEUKOCYTE BIOLOGY

CD137 ligand, a member of the tumor necrosis factor family, regulates immune responses via reverse signal transduction

(2010) Zhe Shao et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Elevated numbers of SCART1+ γδ T cells in skin inflammation and inflammatory bowel disease

(2010) Dorte Rosenbek Fink et al.   MOLECULAR IMMUNOLOGY

Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes

(2010) James F Mohan et al.   NATURE IMMUNOLOGY

Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r null humanized mice

(2010) L. D. Shultz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prolonged antigen survival and cytosolic export in cross-presenting human    T cells

(2010) S. Meuter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Junctional Adhesion Molecule JAML Is a Costimulatory Receptor for Epithelial    T Cell Activation

(2010) D. A. Witherden et al.   SCIENCE

NK Cells and γδ T Cells Mediate Resistance to Polyomavirus–Induced Tumors

(2010) Rabinarayan Mishra et al.   PLoS Pathogens

Zoledronic acid and interleukin-2 treatment improves immunocompetence in HIV-infected persons by activating Vγ9Vδ2 T cells

(2009) Fabrizio Poccia et al.   AIDS

Antigen-restricted γδ T-cell receptors?

(2009) Willi K. Born et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis

(2009) Yoshinaga Ito et al.   ARTHRITIS AND RHEUMATISM

IL-15 produced and trans-presented by DCs underlies homeostatic competition between CD8 and    T cells in vivo

(2009) J.-s. Do et al.   BLOOD

Antitumor Activity of    T Cells Reactive against Cytomegalovirus-Infected Cells in a Mouse Xenograft Tumor Model

(2009) C. Devaud et al.   CANCER RESEARCH

Regression of melanoma metastases following treatment with the n-bisphosphonate zoledronate and localised radiotherapy

(2009) U. Laggner et al.   CLINICAL IMMUNOLOGY

Impact of culture medium on the expansion of T cells for immunotherapy

(2009) Keisuke Sato et al.   CYTOTHERAPY

IL-17-producing γδ T cells

(2009) Rebecca L. O'Brien et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-17-Producing γδ T Cells Selectively Expand in Response to Pathogen Products and Environmental Signals

(2009) Bruno Martin et al.   IMMUNITY

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

(2009) Caroline E. Sutton et al.   IMMUNITY

Human peripheral γδ T cells possess regulatory potential

(2009) Anja A. Kühl et al.   IMMUNOLOGY

Identification and characterization of Foxp3+ γδ T cells in mouse and human

(2009) Ning Kang et al.   IMMUNOLOGY LETTERS

Comparison of phenotype of γδ T cells generated using various cultivation methods

(2009) Stefan Mehrle et al.   IMMUNOLOGY LETTERS

Antigen Specificity of γδ T Cells Depends Primarily on the Flanking Sequences of CDR3δ

(2009) Xueyan Xi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Large scale expansion of Vγ9Vδ2 T lymphocytes from human peripheral blood mononuclear cells after a positive selection using MACS “TCR γ/δ + T cell isolation kit”

(2009) Samuel Salot et al.   JOURNAL OF IMMUNOLOGICAL METHODS

IL-21-Mediated Potentiation of Antitumor Cytolytic and Proinflammatory Responses of Human V 9V 2 T Cells for Adoptive Immunotherapy

(2009) A. Thedrez et al.   JOURNAL OF IMMUNOLOGY

IL-23 Is Required for Protection against Systemic Infection with Listeria monocytogenes

(2009) K. D. Meeks et al.   JOURNAL OF IMMUNOLOGY

Early Triggering of Exclusive IFN-  Responses of Human V 9V 2 T Cells by TLR-Activated Myeloid and Plasmacytoid Dendritic Cells

(2009) M.-C. Devilder et al.   JOURNAL OF IMMUNOLOGY

Activated Human γδ T Cells as Stimulators of Specific CD8+ T-cell Responses to Subdominant Epstein Barr Virus Epitopes

(2009) Silke Landmeier et al.   JOURNAL OF IMMUNOTHERAPY

Phosphoantigen‐Expanded Human γδ T Cells Display Potent Cytotoxicity against Monocyte‐Derived Macrophages Infected with Human and Avian Influenza Viruses

(2009) Gang Qin et al.   JOURNAL OF INFECTIOUS DISEASES

Immunoactivation in preeclampsia: Vδ2+ and regulatory T cells during the inflammatory stage of disease

(2009) Eva Miko et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The cytotoxic protease granzyme M is expressed by lymphocytes of both the innate and adaptive immune system

(2009) Pieter J.A. de Koning et al.   MOLECULAR IMMUNOLOGY

CD27 is a thymic determinant of the balance between interferon-γ- and interleukin 17–producing γδ T cell subsets

(2009) Julie C Ribot et al.   NATURE IMMUNOLOGY

Antigen-specific V 2V 2 T effector cells confer homeostatic protection against pneumonic plaque lesions

(2009) D. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cross-presenting human    T cells induce robust CD8+    T cell responses

(2009) M. Brandes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-Like Receptor Expression and Function in Subsets of Human γδ T Lymphocytes

(2009) K. Pietschmann et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

A Rapid Crosstalk of Human γδ T Cells and Monocytes Drives the Acute Inflammation in Bacterial Infections

(2009) Matthias Eberl et al.   PLoS Pathogens

Phosphoantigen-activated V 2V 2 T cells antagonize IL-2-induced CD4+CD25+Foxp3+ T regulatory cells in mycobacterial infection

(2008) G. Gong et al.   BLOOD

Phase-I study of Innacell γδ™, an autologous cell-therapy product highly enriched in γ9δ2 T lymphocytes, in combination with IL-2, in patients with metastatic renal cell carcinoma

(2008) Jaafar Bennouna et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Mouse γδ T cells are capable of expressing MHC class II molecules, and of functioning as antigen-presenting cells

(2008) Lan Cheng et al.   JOURNAL OF NEUROIMMUNOLOGY