Visualization and functional analysis of the oligomeric states of Escherichia coli heat shock protein 70 (Hsp70/DnaK)

Chemical Screens against a Reconstituted Multiprotein Complex: Myricetin Blocks DnaJ Regulation of DnaK through an Allosteric Mechanism

(2011) Lyra Chang et al.   CHEMISTRY & BIOLOGY

Substrate discrimination of the chaperone BiP by autonomous and cochaperone-regulated conformational transitions

(2011) Moritz Marcinowski et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanics of Hsp70 chaperones enables differential interaction with client proteins

(2011) Rainer Schlecht et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Binding of a Small Molecule at a Protein–Protein Interface Regulates the Chaperone Activity of Hsp70–Hsp40

(2010) Susanne Wisén et al.   ACS Chemical Biology

Death by chaperone: HSP90, HSP70 or both?

(2010) Marissa V. Powers et al.   CELL CYCLE

Mutagenesis Reveals the Complex Relationships between ATPase Rate and the Chaperone Activities ofEscherichia coliHeat Shock Protein 70 (Hsp70/DnaK)

(2010) Lyra Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heat Shock Protein 70 (Hsp70) as an Emerging Drug Target

(2010) Christopher G. Evans et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structural Analysis of the Interactions Between Hsp70 Chaperones and the Yeast DNA Replication Protein Orc4p

(2010) María Moreno-del Álamo et al.   JOURNAL OF MOLECULAR BIOLOGY

Pharmacological Targeting of the Hsp70 Chaperone

(2009) Srikanth Patury et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly

(2009) Yi Xing et al.   EMBO JOURNAL

Solution conformation of wild-type E. coli Hsp70 (DnaK) chaperone complexed with ADP and substrate

(2009) E. B. Bertelsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of small molecules that modify the protein folding activity of heat shock protein 70

(2008) Susanne Wisén et al.   ANALYTICAL BIOCHEMISTRY

Bleach Activates a Redox-Regulated Chaperone by Oxidative Protein Unfolding

(2008) J. Winter et al.   CELL

Structure of the Hsp110:Hsc70 Nucleotide Exchange Machine

(2008) Jonathan P. Schuermann et al.   MOLECULAR CELL

High-throughput screen for small molecules that modulate the ATPase activity of the molecular chaperone DnaK

(2007) Lyra Chang et al.   ANALYTICAL BIOCHEMISTRY