Journal
CELL STEM CELL
Volume 15, Issue 2, Pages 118-120Publisher
CELL PRESS
DOI: 10.1016/j.stem.2014.07.010
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Tumorigenesis is a complex and poorly understood process in which oncogenes can activate competing proapoptotic and proneoplastic programs. A recent paper in Cancer Cell demonstrates a dual role of the MTDH-SND1 complex in suppressing the apoptotic response and promoting breast cancer development, suggesting a new therapeutic avenue.
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