Journal
CELL STEM CELL
Volume 12, Issue 4, Pages 389-390Publisher
CELL PRESS
DOI: 10.1016/j.stem.2013.03.009
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- NICHD NIH HHS [T32 HD007470] Funding Source: Medline
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Two recent studies continue the debate regarding lineage and hierarchy in the intestinal epithelium. One reports that quiescent crypt cells are Paneth cell precursors (Buczacki et al., 2013). The second shows that tamoxifen induces apoptosis in crypt cells and that suppressing apoptosis alters lineage tracing patterns (Zhuet al., 2013).
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