Targeting Th17 cells in immune diseases

Small-Molecule RORγt Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms

(2014) Sheng Xiao et al.   IMMUNITY

Plasticity of TH17 cells in Peyer's patches is responsible for the induction of T cell–dependent IgA responses

(2013) Keiji Hirota et al.   NATURE IMMUNOLOGY

A Validated Regulatory Network for Th17 Cell Specification

(2012) Maria Ciofani et al.   CELL

Transcription of Il17 and Il17f Is Controlled by Conserved Noncoding Sequence 2

(2012) Xiaohu Wang et al.   IMMUNITY

A Protective Role by Interleukin-17F in Colon Tumorigenesis

(2012) Zan Tong et al.   PLoS One

Cigarette Smoke Induction of Osteopontin (SPP1) Mediates TH17 Inflammation in Human and Experimental Emphysema

(2012) M. Shan et al.   Science Translational Medicine

The many faces of Th17 cells

(2011) Anneli Peters et al.   CURRENT OPINION IN IMMUNOLOGY

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

(2010) W. Hueber et al.   Science Translational Medicine

Cutting Edge: In Vitro Generated Th17 Cells Maintain Their Cytokine Expression Program in Normal but Not Lymphopenic Hosts

(2009) R. Nurieva et al.   JOURNAL OF IMMUNOLOGY

Regulation of inflammatory responses by IL-17F

(2008) Xuexian O. Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

(2008) Joshua D. Milner et al.   NATURE