Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells

Targeted Gene Correction Minimally Impacts Whole-Genome Mutational Load in Human-Disease-Specific Induced Pluripotent Stem Cell Clones

(2014) Keiichiro Suzuki et al.   Cell Stem Cell

Low Incidence of Off-Target Mutations in Individual CRISPR-Cas9 and TALEN Targeted Human Stem Cell Clones Detected by Whole-Genome Sequencing

(2014) Adrian Veres et al.   Cell Stem Cell

Whole-Genome Sequencing Analysis Reveals High Specificity of CRISPR/Cas9 and TALEN-Based Genome Editing in Human iPSCs

(2014) Cory Smith et al.   Cell Stem Cell

Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype

(2014) Hao Yin et al.   NATURE BIOTECHNOLOGY

CRISPR technology for gene therapy

(2014)   NATURE MEDICINE

Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA

(2014) C. Long et al.   SCIENCE

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

(2013) Haoyi Wang et al.   CELL

One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering

(2013) Hui Yang et al.   CELL

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting

(2013) Bin Shen et al.   CELL RESEARCH

Genome editing with RNA-guided Cas9 nuclease in Zebrafish embryos

(2013) Nannan Chang et al.   CELL RESEARCH

Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients

(2013) Gerald Schwank et al.   Cell Stem Cell

Correction of a Genetic Disease in Mouse via Use of CRISPR-Cas9

(2013) Yuxuan Wu et al.   Cell Stem Cell

Germline stem cells: toward the regeneration of spermatogenesis

(2013) Hanna Valli et al.   FERTILITY AND STERILITY

TALEN or Cas9 – Rapid, Efficient and Specific Choices for Genome Modifications

(2013) Chuanxian Wei et al.   Journal of Genetics and Genomics

DNA targeting specificity of RNA-guided Cas9 nucleases

(2013) Patrick D Hsu et al.   NATURE BIOTECHNOLOGY

Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems

(2013) Wei Li et al.   NATURE BIOTECHNOLOGY

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

(2013) Vikram Pattanayak et al.   NATURE BIOTECHNOLOGY

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

(2013) Yanfang Fu et al.   NATURE BIOTECHNOLOGY

Heritable gene targeting in the mouse and rat using a CRISPR-Cas system

(2013) Dali Li et al.   NATURE BIOTECHNOLOGY

Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination

(2013) Daniel J Dickinson et al.   NATURE METHODS

Heritable genome editing in C. elegans via a CRISPR-Cas9 system

(2013) Ari E Friedland et al.   NATURE METHODS

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Base-Resolution Analyses of Sequence and Parent-of-Origin Dependent DNA Methylation in the Mouse Genome

(2012) Wei Xie et al.   CELL

Generation of Genetically Modified Mice by Oocyte Injection of Androgenetic Haploid Embryonic Stem Cells

(2012) Hui Yang et al.   CELL

Hypophosphatemia and growth

(2012) Fernando Santos et al.   PEDIATRIC NEPHROLOGY

The Germline Stem Cell Niche Unit in Mammalian Testes

(2012) Jon M. Oatley et al.   PHYSIOLOGICAL REVIEWS

Spermatogonial stem cells, infertility and testicular cancer

(2010) Shree Ram Singh et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A 1-bp deletion in the γC-crystallin leads to dominant cataracts in mice

(2010) Liya Zhao et al.   MAMMALIAN GENOME

Generating knockout rats by transposon mutagenesis in spermatogonial stem cells

(2010) Zsuzsanna Izsvák et al.   NATURE METHODS

Evolution of the mutation rate

(2010) Michael Lynch   TRENDS IN GENETICS

Isolation, Characterization, and Culture of Human Spermatogonia1

(2009) Zuping He et al.   BIOLOGY OF REPRODUCTION

Propagation of Human Spermatogonial Stem Cells In Vitro

(2009) Hooman Sadri-Ardekani   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Capacity for stochastic self-renewal and differentiation in mammalian spermatogonial stem cells

(2009) Zhuoru Wu et al.   JOURNAL OF CELL BIOLOGY

Male Germ Cell Transplantation

(2008) I Dobrinski   REPRODUCTION IN DOMESTIC ANIMALS

Long-Term Culture of Male Germline Stem Cells From Hamster Testes1

(2007) Mito Kanatsu-Shinohara et al.   BIOLOGY OF REPRODUCTION