PKCζ regulates Notch receptor routing and activity in a Notch signaling-dependent manner

Endocytosis by Numb breaks Notch symmetry at cytokinesis

(2012) Lydie Couturier et al.   NATURE CELL BIOLOGY

Notch signaling: simplicity in design, versatility in function

(2011) E. R. Andersson et al.   DEVELOPMENT

Numb Links Extracellular Cues to Intracellular Polarity Machinery to Promote Chemotaxis

(2011) Pengcheng Zhou et al.   DEVELOPMENTAL CELL

The Adaptor-associated Kinase 1, AAK1, Is a Positive Regulator of the Notch Pathway

(2011) Neetu Gupta-Rossi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Numb controls E-cadherin endocytosis through p120 catenin with aPKC

(2011) Kazuhide Sato et al.   MOLECULAR BIOLOGY OF THE CELL

Asymmetric cell divisions promote Notch-dependent epidermal differentiation

(2011) Scott E. Williams et al.   NATURE

aPKC phosphorylates NuMA-related LIN-5 to position the mitotic spindle during asymmetric division

(2011) Matilde Galli et al.   NATURE CELL BIOLOGY

PAR-1 promotes primary neurogenesis and asymmetric cell divisions via control of spindle orientation

(2010) J. M. Tabler et al.   DEVELOPMENT

The vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptor

(2010) T. Vaccari et al.   DEVELOPMENT

ERMES-mediated ER-mitochondria contacts: molecular hubs for the regulation of mitochondrial biology

(2010) B. Kornmann et al.   JOURNAL OF CELL SCIENCE

Protein Kinase Cζ Regulates Cdk5/p25 Signaling during Myogenesis

(2010) Aurélie de Thonel et al.   MOLECULAR BIOLOGY OF THE CELL

γ-Secretase-Dependent Cleavage Initiates Notch Signaling from the Plasma Membrane

(2010) Erika B. Sorensen et al.   TRAFFIC

Polarity and endocytosis: reciprocal regulation

(2010) Jessica M. Shivas et al.   TRENDS IN CELL BIOLOGY

The Translation Initiation Factor 3f (eIF3f) Exhibits a Deubiquitinase Activity Regulating Notch Activation

(2010) Julien Moretti et al.   PLOS BIOLOGY

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

aPKC Phosphorylates Miranda to Polarize Fate Determinants during Neuroblast Asymmetric Cell Division

(2009) Scott X. Atwood et al.   CURRENT BIOLOGY

Endocytic regulation of Notch signaling

(2009) Mark E Fortini et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

PAR-1 Phosphorylates Mind Bomb to Promote Vertebrate Neurogenesis

(2009) Olga Ossipova et al.   DEVELOPMENTAL CELL

The Vacuolar Proton Pump, V-ATPase, Is Required for Notch Signaling and Endosomal Trafficking in Drosophila

(2009) Yan Yan et al.   DEVELOPMENTAL CELL

The multiple functions of Numb

(2009) Alberto Gulino et al.   EXPERIMENTAL CELL RESEARCH

The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis

(2009) L. M. McCaffrey et al.   GENES & DEVELOPMENT

Numb Regulates Post-endocytic Trafficking and Degradation of Notch1

(2009) Melanie A. McGill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An aPKC-Exocyst Complex Controls Paxillin Phosphorylation and Migration through Localised JNK1 Activation

(2009) Carine Rosse et al.   PLOS BIOLOGY

Cdc42, Par6, and aPKC Regulate Arp2/3-Mediated Endocytosis to Control Local Adherens Junction Stability

(2008) Marios Georgiou et al.   CURRENT BIOLOGY

Drosophila Cip4 and WASp Define a Branch of the Cdc42-Par6-aPKC Pathway Regulating E-Cadherin Endocytosis

(2008) Andrea Leibfried et al.   CURRENT BIOLOGY

SoxB1 transcription factors and Notch signaling use distinct mechanisms to regulate proneural gene function and neural progenitor differentiation

(2008) J. Holmberg et al.   DEVELOPMENT

Drosophila HOPS and AP-3 Complex Genes Are Required for a Deltex-Regulated Activation of Notch in the Endosomal Trafficking Pathway

(2008) Marian Wilkin et al.   DEVELOPMENTAL CELL

Endosomal entry regulates Notch receptor activation inDrosophila melanogaster

(2008) Thomas Vaccari et al.   JOURNAL OF CELL BIOLOGY