Deficiency of IRTKS as an adaptor of insulin receptor leads to insulin resistance

Loss of Estrogen Receptor a Signaling Leads to Insulin Resistance and Obesity in Young and Adult Female Mice

(2012) Camila Manrique et al.   CardioRenal Medicine

Functional analysis ofDictyosteliumIBARa reveals a conserved role of the I-BAR domain in endocytosis

(2011) Douwe M. Veltman et al.   BIOCHEMICAL JOURNAL

Hypermethylation of Hepatic Glucokinase and L-Type Pyruvate Kinase Promoters in High-Fat Diet–Induced Obese Rats

(2011) Minghong Jiang et al.   ENDOCRINOLOGY

Insulin Receptor Tyrosine Kinase Substrate Enhances Low Levels of MDM2-Mediated p53 Ubiquitination

(2011) Ke-Sheng Wang et al.   PLoS One

I-BAR domain proteins: linking actin and plasma membrane dynamics

(2010) Hongxia Zhao et al.   CURRENT OPINION IN CELL BIOLOGY

Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

(2010) Sheau-Fang Ng et al.   NATURE

Recognition of tandem PxxP motifs as a unique Src homology 3-binding mode triggers pathogen-driven actin assembly

(2010) O. Aitio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of the peroxisome proliferator activated receptor gamma gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes

(2009) Katsunori Fujiki et al.   BMC BIOLOGY

Molecular Mechanisms of Membrane Deformation by I-BAR Domain Proteins

(2009) Juha Saarikangas et al.   CURRENT BIOLOGY

Epigenetics: A Molecular Link Between Environmental Factors and Type 2 Diabetes

(2009) Charlotte Ling et al.   DIABETES

The Insulin Receptor Substrate of 53 kDa (IRSp53) Limits Hippocampal Synaptic Plasticity

(2009) Corinna Sawallisch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhanced NMDA Receptor-Mediated Synaptic Transmission, Enhanced Long-Term Potentiation, and Impaired Learning and Memory in Mice Lacking IRSp53

(2009) M.-H. Kim et al.   JOURNAL OF NEUROSCIENCE

High fat diet-induced obesity modifies the methylation pattern of leptin promoter in rats

(2009) F. I. Milagro et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathwaysin vivo

(2009) Valérie F. Crepin et al.   MOLECULAR MICROBIOLOGY

Influence of menopause on diabetes and diabetes risk

(2009) Emily D. Szmuilowicz et al.   Nature Reviews Endocrinology

Epigenetic mechanisms that underpin metabolic and cardiovascular diseases

(2009) Peter D. Gluckman et al.   Nature Reviews Endocrinology

Insulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspFU during pedestal formation

(2009) D. Vingadassalom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

I-BAR domains, IRSp53 and filopodium formation

(2009) Sohail Ahmed et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Subcellular membrane curvature mediated by the BAR domain superfamily proteins

(2009) Shiro Suetsugu et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Identification of the insulin-responsive tyrosine phosphorylation sites on IRSp53

(2008) M HEUNG et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

IRSp53: crossing the road of membrane and actin dynamics in the formation of membrane protrusions

(2008) Giorgio Scita et al.   TRENDS IN CELL BIOLOGY

The development of insulin resistance in Type 2 diabetes: insights from knockout studies

(2008) Ratchada Pattaranit et al.   SCIENCE PROGRESS