PICK1 promotes caveolin-dependent degradation of TGF-β type I receptor

The TGF-β co-receptor, CD109, promotes internalization and degradation of TGF-β receptors

(2011) Albane A. Bizet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Protein interacting with C α kinase 1 (PICK1) is involved in promoting tumor growth and correlates with poor prognosis of human breast cancer

(2010) Bin Zhang et al.   CANCER SCIENCE

Loss of Dact1 Disrupts Planar Cell Polarity Signaling by Altering Dishevelled Activity and Leads to Posterior Malformation in Mice

(2010) Jun Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation

(2010) Chan Gao et al.   NATURE CELL BIOLOGY

Human BAMBI Cooperates with Smad7 to Inhibit Transforming Growth Factor-β Signaling

(2009) Xiaohua Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PICK1 deficiency causes male infertility in mice by disrupting acrosome formation

(2009) Nan Xiao et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD

(2009) T. S. Thorsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New regulatory mechanisms of TGF-β receptor function

(2009) Jong Seok Kang et al.   TRENDS IN CELL BIOLOGY

Modulation of d-Serine Levels in Brains of Mice Lacking PICK1

(2008) Takatoshi Hikida et al.   BIOLOGICAL PSYCHIATRY

TGFβ in Cancer

(2008) Joan Massagué   CELL

Endocytic regulation of TGF-β signaling

(2008) Ye-Guang Chen   CELL RESEARCH

Regulating the stability of TGFβ receptors and Smads

(2008) Peter Lönn et al.   CELL RESEARCH

Specific Activation of Mitogen-activated Protein Kinase by Transforming Growth Factor-β Receptors in Lipid Rafts Is Required for Epithelial Cell Plasticity

(2008) Wei Zuo et al.   MOLECULAR BIOLOGY OF THE CELL

Inhibition of Arp2/3-mediated actin polymerization by PICK1 regulates neuronal morphology and AMPA receptor endocytosis

(2008) Daniel L. Rocca et al.   NATURE CELL BIOLOGY

PICK1: A multi-talented modulator of AMPA receptor trafficking

(2008) Jonathan G. Hanley   PHARMACOLOGY & THERAPEUTICS