Signal control through Raf: in sickness and in health

Cell of Origin of Small Cell Lung Cancer: Inactivation of Trp53 and Rb1 in Distinct Cell Types of Adult Mouse Lung

(2011) Kate D. Sutherland et al.   CANCER CELL

RAF Inhibitor-Induced KSR1/B-RAF Binding and Its Effects on ERK Cascade Signaling

(2011) Melissa M. McKay et al.   CURRENT BIOLOGY

MAPK Phosphatase-1 (MKP-1) Expression Is Up-Regulated by hCG/cAMP and Modulates Steroidogenesis in MA-10 Leydig Cells

(2011) Laura Brion et al.   ENDOCRINOLOGY

ERK and PDE4 cooperate to induce RAF isoform switching in melanoma

(2011) Amélie Marquette et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF

(2010) Sonja J. Heidorn et al.   CELL

KSR1 is a functional protein kinase capable of serine autophosphorylation and direct phosphorylation of MEK1

(2010) Jeremy A. Goettel et al.   EXPERIMENTAL CELL RESEARCH

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

(2010) Poulikos I. Poulikakos et al.   NATURE

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

(2010) Georgia Hatzivassiliou et al.   NATURE

AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade

(2010) F. Donelson Smith et al.   NATURE CELL BIOLOGY

Calcineurin increases glucose activation of ERK1/2 by reversing negative feedback

(2010) L. Duan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

KSR2 Is an Essential Regulator of AMP Kinase, Energy Expenditure, and Insulin Sensitivity

(2009) Diane L. Costanzo-Garvey et al.   Cell Metabolism

Radial Spoke Protein 3 Is a Mammalian Protein Kinase A-anchoring Protein That Binds ERK1/2

(2009) Arif Jivan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impact of Feedback Phosphorylation and Raf Heterodimerization on Normal and Mutant B-Raf Signaling

(2009) D. A. Ritt et al.   MOLECULAR AND CELLULAR BIOLOGY

KSR2 Is a Calcineurin Substrate that Promotes ERK Cascade Activation in Response to Calcium Signals

(2009) Michele K. Dougherty et al.   MOLECULAR CELL

IMP Modulates KSR1-dependent Multivalent Complex Formation to Specify ERK1/2 Pathway Activation and Response Thresholds

(2008) Chiyuan Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

(2008) J. Tsai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA