Journal
CELL METABOLISM
Volume 17, Issue 6, Pages 809-811Publisher
CELL PRESS
DOI: 10.1016/j.cmet.2013.05.014
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The mechanisms underlying the biological activity of metformin, a widely prescribed drug to treat type 2 diabetes, remain elusive. In a recent issue of Cell, Cabreiro et al. report that in C. elegans, metformin indirectly impacts lifespan by altering the methionine metabolism of its microbial partner E. coli (Cabreiro et al., 2013).
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