Journal
CELL METABOLISM
Volume 9, Issue 3, Pages 211-212Publisher
CELL PRESS
DOI: 10.1016/j.cmet.2009.02.004
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- NIDDK NIH HHS [R01 DK063016] Funding Source: Medline
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The mechanism by which HFE participates in the regulation of iron homeostasis has remained enigmatic. Gao et al. (2009) make the key discovery that the regulation of hepcidin in response to holotransferrin requires the interaction between HFE and transferrin receptor 2 (TfR2).
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