Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase

Self-consumption: the interplay of autophagy and apoptosis

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Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase

(2013) Yoshio Nakatani et al.   BIOCHEMICAL JOURNAL

RabGEFs are a major determinant for specific Rab membrane targeting

(2013) Julia Blümer et al.   JOURNAL OF CELL BIOLOGY

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

(2013) Shireen A. Sarraf et al.   NATURE

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes

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Modulation of Serines 17 and 24 in the LC3-interacting Region of Bnip3 Determines Pro-survival MitophagyversusApoptosis

(2012) Yanyan Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy

(2012) Rita A. Hanna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of ubiquitylation in receptor endocytosis and endosomal sorting

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Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

(2012) Lei Liu et al.   NATURE CELL BIOLOGY

Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling

(2012) Joshua J Sims et al.   NATURE METHODS

The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax

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Bid-induced mitochondrial membrane permeabilization waves propagated by local reactive oxygen species (ROS) signaling

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HIV-1 Nef compensates for disorganization of the immunological synapse by inducing trans-Golgi network-associated Lck signaling

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Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy

(2011) T. N. Chonghaile et al.   SCIENCE

Bioenergetics and cell death

(2010) Yulia Kushnareva et al.   Annals of the New York Academy of Sciences

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

XIAP impairs Smac release from the mitochondria during apoptosis

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Role of BNIP3 and NIX in cell death, autophagy and mitophagy

(2009) J Zhang et al.   CELL DEATH AND DIFFERENTIATION

XIAP as a ubiquitin ligase in cellular signaling

(2009) S Galbán et al.   CELL DEATH AND DIFFERENTIATION

Dynamics of outer mitochondrial membrane permeabilization during apoptosis

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Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL

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Nix is a selective autophagy receptor for mitochondrial clearance

(2009) Ivana Novak et al.   EMBO REPORTS

Role for X-linked Inhibitor of Apoptosis Protein Upstream of Mitochondrial Permeabilization

(2009) Thomas W. Owens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

XIAP discriminates between type I and type II FAS-induced apoptosis

(2009) Philipp J. Jost et al.   NATURE

Ubiquitin binding and conjugation regulate the recruitment of Rabex-5 to early endosomes

(2008) Rafael Mattera et al.   EMBO JOURNAL

Regulation of apoptosis by XIAP ubiquitin-ligase activity

(2008) A. J. Schile et al.   GENES & DEVELOPMENT

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Essential role for Nix in autophagic maturation of erythroid cells

(2008) Hector Sandoval et al.   NATURE

Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

(2008) P. K. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA