PARP inhibitors and IR join forces to strike glioblastoma-initiating cells

PARP inhibitors bounce back

(2013) Ken Garber   NATURE REVIEWS DRUG DISCOVERY

Ionizing Radiation in Glioblastoma Initiating Cells

(2013) Maricruz Rivera et al.   Frontiers in Oncology

Role of PARP Inhibitors in Cancer Biology and Therapy

(2012) D. Davar et al.   CURRENT MEDICINAL CHEMISTRY

Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner

(2011) Janel E. Le Belle et al.   Cell Stem Cell

The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings

(2011) Thomas Helleday   Molecular Oncology

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Association of reactive oxygen species levels and radioresistance in cancer stem cells

(2009) Maximilian Diehn et al.   NATURE

Cellular responses to reactive oxygen species-induced DNA damage and aging

(2008) Catharina Bertram et al.   BIOLOGICAL CHEMISTRY