4.4 Article

Differential expression of two C-type lectins in grass carp Ctenopharyngodon idella and their response to grass carp reovirus

Journal

JOURNAL OF FISH BIOLOGY
Volume 88, Issue 2, Pages 787-793

Publisher

WILEY
DOI: 10.1111/jfb.12815

Keywords

galactose-binding lectin; group III lectins; mannose-binding lectin; maternal expression pattern

Funding

  1. National High Technology Research and Development Programme [2011AA100403]
  2. National Natural Science Foundation of China [31130055]
  3. Independent project of State Key Laboratory of Freshwater Ecology and Biotechnology [2014FBZ04]
  4. Direction Programme of Chinese Academy of Sciences [KSCX2-EW-N-004-3]

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The cDNAs of two C-type lectins in grass carp Ctenopharyngodon idella, galactose-binding lectin (galbl) and mannose-binding lectin (mbl), were cloned and analysed in this study. Both of them exhibited the highest expression level in liver, whereas their expression pattern differed in early phase of embryonic development. Following exposure to grass carp reovirus (GCRV), the mRNA expression level of galbl and mbl was significantly up-regulated in liver and intestine.

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