Grail as a molecular determinant for the functions of the tumor suppressor p53 in tumorigenesis

p21WAF1is component of a positive feedback loop that maintains the p53 transcriptional program

(2011) Lisa Y. Pang et al.   CELL CYCLE

GRAIL: a unique mediator of CD4 T-lymphocyte unresponsiveness

(2010) Chan C. Whiting et al.   FEBS Journal

The E3 Ubiquitin Ligase GRAIL Regulates T Cell Tolerance and Regulatory T Cell Function by Mediating T Cell Receptor-CD3 Degradation

(2010) Roza I. Nurieva et al.   IMMUNITY

Sustained Expression of GRAIL during Hematopoiesis Results in Dysregulated Differentiation

(2009) Debra A. MacKenzie et al.   ACTA HAEMATOLOGICA

Naive CD4 T Cell Proliferation Is Controlled by Mammalian Target of Rapamycin Regulation of GRAIL Expression

(2009) Jack T. Lin et al.   JOURNAL OF IMMUNOLOGY

The Transmembrane E3 Ligase GRAIL Ubiquitinates and Degrades CD83 on CD4 T Cells

(2009) L. L. Su et al.   JOURNAL OF IMMUNOLOGY

The Single Subunit Transmembrane E3 Ligase Gene Related to Anergy in Lymphocytes (GRAIL) Captures and Then Ubiquitinates Transmembrane Proteins across the Cell Membrane

(2008) Neil Lineberry et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of the E3 ubiquitin ligase gene related to anergy in lymphocytes in glucose and lipid metabolism in the liver

(2008) Sachie Nakamichi et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Modulation of the Cyclin-Dependent Kinase Inhibitor p21WAF1/Cip1 Gene by Zac1 through the Antagonistic Regulators p53 and Histone Deacetylase 1 in HeLa Cells

(2008) P.-Y. Liu et al.   MOLECULAR CANCER RESEARCH

Epigenetic Changes and Suppression of the Nuclear Factor of Activated T Cell 1 (NFATC1) Promoter in Human Lymphomas with Defects in Immunoreceptor Signaling

(2007) Askar Akimzhanov et al.   AMERICAN JOURNAL OF PATHOLOGY