Epigenetic silencing of Bim transcription by Spi-1/PU.1 promotes apoptosis resistance in leukaemia

Cotargeting signaling pathways driving survival and cell cycle circumvents resistance to Kit inhibitors in leukemia

(2012) D. Buet et al.   BLOOD

Emerging roles of the spliceosomal machinery in myelodysplastic syndromes and other hematological disorders

(2012) V Visconte et al.   LEUKEMIA

Direct Recruitment of Polycomb Repressive Complex 1 to Chromatin by Core Binding Transcription Factors

(2012) Ming Yu et al.   MOLECULAR CELL

Spi-1/PU.1 activates transcription through clustered DNA occupancy in erythroleukemia

(2012) Maya Ridinger-Saison et al.   NUCLEIC ACIDS RESEARCH

Spi-1, Fli-1 and Fli-3 (miR-17-92) Oncogenes Contribute to a Single Oncogenic Network Controlling Cell Proliferation in Friend Erythroleukemia

(2012) Samer Kayali et al.   PLoS One

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases

(2011) Andreas Strasser et al.   EMBO JOURNAL

Epigenetic silencing of the oncogenic miR-17-92 cluster during PU.1-directed macrophage differentiation

(2011) Vit Pospisil et al.   EMBO JOURNAL

A Unified Model of Mammalian BCL-2 Protein Family Interactions at the Mitochondria

(2011) Fabien Llambi et al.   MOLECULAR CELL

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

Polycomb proteins in hematologic malignancies

(2010) D. Martin-Perez et al.   BLOOD

Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma

(2010) J. A. Richter-Larrea et al.   BLOOD

Spi-1/PU.1 Oncogene Accelerates DNA Replication Fork Elongation and Promotes Genetic Instability in the Absence of DNA Breakage

(2010) P. Rimmele et al.   CANCER RESEARCH

Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer

(2010) Martin Sauvageau et al.   Cell Stem Cell

Tumorigenicity of the miR-17-92 cluster distilled

(2010) G. van Haaften et al.   GENES & DEVELOPMENT

Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages

(2010) Serena Ghisletti et al.   IMMUNITY

The BCL-2 Family Reunion

(2010) Jerry E. Chipuk et al.   MOLECULAR CELL

Short RNAs Are Transcribed from Repressed Polycomb Target Genes and Interact with Polycomb Repressive Complex-2

(2010) Aditi Kanhere et al.   MOLECULAR CELL

Polycomb protein EZH2 regulates E2F1-dependent apoptosis through epigenetically modulating Bim expression

(2009) Z L Wu et al.   CELL DEATH AND DIFFERENTIATION

The Role of Apoptosis in Cancer Development and Treatment: Focusing on the Development and Treatment of Hematologic Malignancies

(2009) J. Zivny et al.   CURRENT PHARMACEUTICAL DESIGN

Epigenetic down-regulation of BIM expression is associated with reduced optimal responses to imatinib treatment in chronic myeloid leukaemia

(2009) Edurne San José-Eneriz et al.   EUROPEAN JOURNAL OF CANCER

The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukemic transformation

(2009) H. Boukarabila et al.   GENES & DEVELOPMENT

Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis

(2009) Ming Yu et al.   MOLECULAR CELL

Epstein-Barr Virus Latency in B Cells Leads to Epigenetic Repression and CpG Methylation of the Tumour Suppressor Gene Bim

(2009) Kostas Paschos et al.   PLoS Pathogens

Erythropoietin-induced phosphorylation/degradation of BIM contributes to survival of erythroid cells

(2008) Randolph M. Abutin et al.   EXPERIMENTAL HEMATOLOGY

Cooperating gene mutations in acute myeloid leukemia: a review of the literature

(2008) A Renneville et al.   LEUKEMIA

Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome

(2008) J. Zhao et al.   SCIENCE

Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains

(2008) Manching Ku et al.   PLoS Genetics

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY