T-cell death following immune activation is mediated by mitochondria-localized SARM

Cutting Edge: Antigen Presentation to CD8 T Cells after Influenza A Virus Infection

(2014) E. Ingulli et al.   JOURNAL OF IMMUNOLOGY

Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis

(2012) Jerry E. Chipuk et al.   CELL

dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway

(2012) J. M. Osterloh et al.   SCIENCE

Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: definition of the critical region and residues in the signal sequence

(2011) Porkodi Panneerselvam et al.   BIOCHEMICAL JOURNAL

Targeting the Extracellular Signal-Regulated Kinase Pathway in Cancer Therapy

(2011) Michiaki Kohno et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol

(2011) Frank Edlich et al.   CELL

Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics

(2011) Jean-Claude Martinou et al.   DEVELOPMENTAL CELL

Regulation of Anoxic Death in Caenorhabditis elegans by Mammalian Apoptosis Signal-Regulating Kinase (ASK) Family Proteins

(2011) T. Hayakawa et al.   GENETICS

Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology

(2011) Chiung-Ya Chen et al.   JOURNAL OF CELL BIOLOGY

Mcl-1 promotes survival of thymocytes by inhibition of Bak in a pathway separate from Bcl-2

(2010) A Dunkle et al.   CELL DEATH AND DIFFERENTIATION

SARM inhibits both TRIF- and MyD88-mediated AP-1 activation

(2010) Jun Peng et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Activated oncogenic pathways and therapeutic targets in extranodal nasal-type NK/T cell lymphoma revealed by gene expression profiling

(2010) Siok-Bian Ng et al.   JOURNAL OF PATHOLOGY

Toll-like receptors and innate immunity

(2009) Himanshu Kumar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial calcium and the permeability transition in cell death

(2009) John J. Lemasters et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Gene expression profiling identifies emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal type

(2009) Y. Huang et al.   BLOOD

The Immune Adaptor Molecule SARM Modulates Tumor Necrosis Factor Alpha Production and Microglia Activation in the Brainstem and Restricts West Nile Virus Pathogenesis

(2009) K. J. Szretter et al.   JOURNAL OF VIROLOGY

Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition

(2009) A. Rasola et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Death by Committee: Organellar Trafficking and Communication in Apoptosis

(2009) Joseph E. Aslan et al.   TRAFFIC

Concepts of activated T cell death

(2008) Dirk Brenner et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

(2008) Jerry E. Chipuk et al.   TRENDS IN CELL BIOLOGY

SARM: a novel Toll-like receptor adaptor, is functionally conserved from arthropod to human

(2007) Loh Wei-Ching Belinda et al.   MOLECULAR IMMUNOLOGY