Perforin deficiency and susceptibility to cancer

Familial Hemophagocytic Lymphohistiocytosis Type 5 (FHL-5) Is Caused by Mutations in Munc18-2 and Impaired Binding to Syntaxin 11

(2009) Udo zur Stadt et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Molecular Basis for Perforin Oligomerization and Transmembrane Pore Assembly

(2009) Katherine Baran et al.   IMMUNITY

Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells

(2009) Marjorie Côte et al.   JOURNAL OF CLINICAL INVESTIGATION

Demyelinated Axons and Motor Function Are Protected by Genetic Deletion of Perforin in a Mouse Model of Multiple Sclerosis

(2009) Chandra Deb et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Temperature sensitivity of human perforin mutants unmasks subtotal loss of cytotoxicity, delayed FHL, and a predisposition to cancer

(2009) J. Chia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cleavage of La protein by granzyme H induces cytoplasmic translocation and interferes with La-mediated HCV-IRES translational activity

(2008) V Romero et al.   CELL DEATH AND DIFFERENTIATION

The MACPF/CDC family of pore-forming toxins

(2008) Carlos J. Rosado et al.   CELLULAR MICROBIOLOGY

Variations of the perforin gene in patients with multiple sclerosis

(2008) G Cappellano et al.   GENES AND IMMUNITY

Hemophagocytic Lymphohistiocytosis and Other Hemophagocytic Disorders

(2008) Alexandra H. Filipovich   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Crystal Structure of the MACPF Domain of Human Complement Protein C8α in Complex with the C8γ Subunit

(2008) Daniel J. Slade et al.   JOURNAL OF MOLECULAR BIOLOGY