Reinforcing targeted therapeutics with phenotypic stability factors

Mammary Morphogenesis and Regeneration Require the Inhibition of EMT at Terminal End Buds by Ovol2 Transcriptional Repressor

(2014) Kazuhide Watanabe et al.   DEVELOPMENTAL CELL

Notch-1 Signaling Promotes the Malignant Features of Human Breast Cancer through NF-κB Activation

(2014) Li Li et al.   PLoS One

Breast cancer stem cells: Obstacles to therapy

(2012) Matthew Smalley et al.   CANCER LETTERS

The specific role of pRb in p16INK4A-mediated arrest of normal and malignant human breast cells

(2012) Alexey V. Bazarov et al.   CELL CYCLE

Breast Cancer Stem Cells: A Novel Therapeutic Target

(2012) Sudeshna Gangopadhyay et al.   Clinical Breast Cancer

Cdk4/6 Inhibition Induces Epithelial-Mesenchymal Transition and Enhances Invasiveness in Pancreatic Cancer Cells

(2012) F. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways

(2012) D. Horiuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-canonical Notch signaling: emerging role and mechanism

(2012) Peter Andersen et al.   TRENDS IN CELL BIOLOGY

Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence

(2011) K Pandya et al.   BRITISH JOURNAL OF CANCER

Cyclin E amplification/overexpression is a mechanism of trastuzumab resistance in HER2+breast cancer patients

(2011) Maurizio Scaltriti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibiting NF-κB activation by small molecules as a therapeutic strategy

(2010) Subash C. Gupta et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Sequential Activation of NFAT and c-Myc Transcription Factors Mediates the TGF-β Switch from a Suppressor to a Promoter of Cancer Cell Proliferation

(2010) Garima Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Notch Signaling Pathway as a Therapeutic Target in Breast Cancer

(2010) H. Al-Hussaini et al.   MOLECULAR CANCER THERAPEUTICS

A novel interaction between HER2/neu and cyclin E in breast cancer

(2010) E A Mittendorf et al.   ONCOGENE

Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure

(2010) J L Dean et al.   ONCOGENE

An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation

(2009) Dimitrios Iliopoulos et al.   CELL

p21 and p27: roles in carcinogenesis and drug resistance

(2008) Abde M. Abukhdeir et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

G1 arrest and expression of cyclin-dependent kinase inhibitors in tamoxifen-treated MCF-7 human breast cancer cells

(2008) Akira ICHIKAWA et al.   Human Cell