Spatial regulation of Aurora A activity during mitotic spindle assembly requires RHAMM to correctly localize TPX2

Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition.

(2015) Pooja Mohan et al.   Oncotarget

Bora and Aurora-A continue to activate Plk1 in mitosis

(2013) Wytse Bruinsma et al.   JOURNAL OF CELL SCIENCE

The Cytoskeletal Protein RHAMM and ERK1/2 Activity Maintain the Pluripotency of Murine Embryonic Stem Cells

(2013) Jihong Jiang et al.   PLoS One

Polo-like kinase-activating kinases

(2012) Vincent Archambault et al.   CELL CYCLE

Polo-like kinase-1 regulates kinetochore–microtubule dynamics and spindle checkpoint silencing

(2012) Dan Liu et al.   JOURNAL OF CELL BIOLOGY

Dynein light chain 1 and a spindle-associated adaptor promote dynein asymmetry and spindle orientation

(2012) Anja K. Dunsch et al.   JOURNAL OF CELL BIOLOGY

Aurora kinase-A regulates kinetochore/chromatin associated microtubule assembly in human cells

(2011) Hiroshi Katayama et al.   CELL CYCLE

Phosphorylation of TPX2 by Plx1 enhances activation of Aurora A

(2011) Frank Eckerdt et al.   CELL CYCLE

A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging

(2011) Daniel G Booth et al.   EMBO JOURNAL

Activation of Aurora-A Kinase by Protein Partner Binding and Phosphorylation Are Independent and Synergistic

(2011) Charlotte A. Dodson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional analysis of the microtubule-interacting transcriptome

(2011) Judith A. Sharp et al.   MOLECULAR BIOLOGY OF THE CELL

Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer

(2011) Christopher A. Maxwell et al.   PLOS BIOLOGY

Centrosome Size Sets Mitotic Spindle Length in Caenorhabditis elegans Embryos

(2010) Garrett Greenan et al.   CURRENT BIOLOGY

Novel Binding of the Mitotic Regulator TPX2 (Target Protein forXenopusKinesin-like Protein 2) to Importin-α

(2010) Astrid Giesecke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RHAMM Promotes Interphase Microtubule Instability and Mitotic Spindle Integrity through MEK1/ERK1/2 Activity

(2010) Cornelia Tolg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2

(2010) Kang Zeng et al.   JOURNAL OF CELL BIOLOGY

Control of Aurora-A stability through interaction with TPX2

(2010) M. Giubettini et al.   JOURNAL OF CELL SCIENCE

Regulated Degradation of Spindle Assembly Factors by the Anaphase-Promoting Complex

(2010) Ling Song et al.   MOLECULAR CELL

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

(2010) Beate Neumann et al.   NATURE

Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A

(2008) Alexander W. Bird et al.   JOURNAL OF CELL BIOLOGY

The RanGTP gradient - a GPS for the mitotic spindle

(2008) P. Kalab et al.   JOURNAL OF CELL SCIENCE

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery

(2008) Libor Macůrek et al.   NATURE