Inhibition of histone deacetylases enhances DNA damage repair in SCNT embryos

Laser microbeam-induced DNA damage inhibits cell division in fertilized eggs and early embryos

(2013) Zhong-Wei Wang et al.   CELL CYCLE

Histone Acetyltransferase 1 Promotes Homologous Recombination in DNA Repair by Facilitating Histone Turnover

(2013) Xiaohan Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kinetics of nuclear phosphorylation ( -H2AX) in human lymphocytes treated in vitro with UVB, bleomycin and mitomycin C

(2013) R. Scarpato et al.   MUTAGENESIS

Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination

(2013) Jiangbo Tang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mouse Zygotes Respond to Severe Sperm DNA Damage by Delaying Paternal DNA Replication and Embryonic Development

(2013) Joanna E. Gawecka et al.   PLoS One

Phosphorylated histone H2A.x in porcine embryos produced by IVF and somatic cell nuclear transfer

(2013) Rodrigo C Bohrer et al.   REPRODUCTION

Brief Report: Impaired Cell Reprogramming in Nonhomologous End Joining Deficient Cells

(2013) F. Javier Molina-Estevez et al.   STEM CELLS

Synergistic effect of trichostatin A and scriptaid on the development of cloned rabbit embryos

(2013) C.H. Chen et al.   THERIOGENOLOGY

Homologous Recombination DNA Repair Genes Play a Critical Role in Reprogramming to a Pluripotent State

(2013) Federico González et al.   Cell Reports

The DNA damage response in mammalian oocytes

(2013) John Carroll et al.   Frontiers in Genetics

Combination therapy: Histone deacetylase inhibitors and platinum-based chemotherapeutics for cancer

(2012) Himashinie V.K. Diyabalanage et al.   CANCER LETTERS

Homologous recombination and non-homologous end-joining repair pathways in bovine embryos with different developmental competence

(2012) Marcos Henrique Barreta et al.   EXPERIMENTAL CELL RESEARCH

DNA Damage-Sensing Kinases Mediate the Mouse 2-Cell Embryo's Response to Genotoxic Stress

(2011) X. F. Mu et al.   BIOLOGY OF REPRODUCTION

Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer

(2011) Raffaella Di Micco et al.   NATURE CELL BIOLOGY

Analysis of Imprinted Gene Expression in Normal Fertilized and Uniparental Preimplantation Porcine Embryos

(2011) Chi-Hun Park et al.   PLoS One

Role of checkpoint kinase 1 (Chk1) in the mechanisms of resistance to histone deacetylase inhibitors

(2011) J.-H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pre- and Postimplantation Development of Swine-Cloned Embryos Derived from Fibroblasts and Bone Marrow Cells after Inhibition of Histone Deacetylases

(2010) Mario A. Martinez-Diaz et al.   Cellular Reprogramming

Histone Deacetylase Inhibitors Improve In Vitro and In Vivo Developmental Competence of Somatic Cell Nuclear Transfer Porcine Embryos

(2010) Jianguo Zhao et al.   Cellular Reprogramming

Chromatin in early mammalian embryos: achieving the pluripotent state

(2010) Helena Fulka et al.   DIFFERENTIATION

UV-induced histone H2AX phosphorylation and DNA damage related proteins accumulate and persist in nucleotide excision repair-deficient XP-B cells

(2010) Kyu-Seon Oh et al.   DNA REPAIR

A cooperative activation loop among SWI/SNF, γ-H2AX and H3 acetylation for DNA double-strand break repair

(2010) Han-Sae Lee et al.   EMBO JOURNAL

HDACi - going through the mechanisms

(2010) Malgorzata Wanczyk   Frontiers in Bioscience-Landmark

Treatment with a Histone Deacetylase Inhibitor after Nuclear Transfer Improves the Preimplantation Development of Cloned Bovine Embryos

(2010) Satoshi AKAGI et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

MOF and Histone H4 Acetylation at Lysine 16 Are Critical for DNA Damage Response and Double-Strand Break Repair

(2010) G. G. Sharma et al.   MOLECULAR AND CELLULAR BIOLOGY

Pathways of mammalian replication fork restart

(2010) Eva Petermann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A minority of foci or pan-nuclear apoptotic staining of  H2AX in the S phase after UV damage contain DNA double-strand breaks

(2010) S. de Feraudy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone deacetylase inhibitor induces DNA damage, which normal but not transformed cells can repair

(2010) J.- H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Significant Improvement in Cloning Efficiency of an Inbred Miniature Pig by Histone Deacetylase Inhibitor Treatment after Somatic Cell Nuclear Transfer1

(2009) Jianguo Zhao et al.   BIOLOGY OF REPRODUCTION

Trichostatin A treatment of cloned mouse embryos improves constitutive heterochromatin remodeling as well as developmental potential to term

(2009) Walid E Maalouf et al.   BMC DEVELOPMENTAL BIOLOGY

Histone deacetylase inhibitors: Potential in cancer therapy

(2009) P.A. Marks et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

(2009) Rosa M. Marión et al.   NATURE

The histone deacetylase inhibitor scriptaid enhances nascent mRNA production and rescues full-term development in cloned inbred mice

(2009) Nguyen Van Thuan et al.   REPRODUCTION

Effect of trychostatin A treatment on gene expression in cloned mouse embryos

(2009) G.-B. Shao et al.   THERIOGENOLOGY

The cytoplasm of mouse germinal vesicle stage oocytes can enhance somatic cell nuclear reprogramming

(2008) H.-T. Bui et al.   DEVELOPMENT

Kinetics of γ-H2AX focus formation upon treatment of cells with UV light and alkylating agents

(2008) Ori Staszewski et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

(2008) Nadya Dimitrova et al.   NATURE

Epigenetic reprogramming in embryonic and foetal development upon somatic cell nuclear transfer cloning

(2008) Heiner Niemann et al.   REPRODUCTION

The Effects of Trichostatin A on mRNA Expression of Chromatin Structure-, DNA Methylation-, and Development-Related Genes in Cloned Mouse Blastocysts

(2008) Xiangping Li et al.   Cloning Stem Cells

Trichostatin A Improves Histone Acetylation in Bovine Somatic Cell Nuclear Transfer Early Embryos

(2008) Amy E. Iager et al.   Cloning Stem Cells