The anaphase-promoting complex/cyclosome is an E3 ubiquitin ligase for Mdm2

Regulation of Mdm2 protein stability and the p53 response by NEDD4-1 E3 ligase

(2014) C Xu et al.   ONCOGENE

Pharmacologic Inhibition of the Anaphase-Promoting Complex Induces A Spindle Checkpoint-Dependent Mitotic Arrest in the Absence of Spindle Damage

(2010) Xing Zeng et al.   CANCER CELL

Phosphorylation by Casein Kinase I Promotes the Turnover of the Mdm2 Oncoprotein via the SCFβ-TRCP Ubiquitin Ligase

(2010) Hiroyuki Inuzuka et al.   CANCER CELL

Unlocking the Mdm2-p53 loop: Ubiquitin is the key

(2010) Hilary V. Clegg et al.   CELL CYCLE

The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor

(2010) J. J. Manfredi   GENES & DEVELOPMENT

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

MDM2 Gene Amplification Is Correlated to Tumor Progression but not to the Presence of SNP309 or TP53 Mutational Status in Primary Colorectal Cancers

(2008) A. Forslund et al.   MOLECULAR CANCER RESEARCH