A novel mechanism of crosstalk between the p53 and NFκB pathways

Network Modeling of MDM2 Inhibitor-Oxaliplatin Combination Reveals Biological Synergy in wt-p53 solid tumors

(2015) Asfar S. Azmi et al.   Oncotarget

cIAP2 represses IKKα/β-mediated activation of MDM2 to prevent p53 degradation

(2012) Rosanna Lau et al.   CELL CYCLE

Autophagy is required for the activation of NFκB

(2012) Alfredo Criollo et al.   CELL CYCLE

Monoubiquitination of nuclear RelA negatively regulates NF-κB activity independent of proteasomal degradation

(2012) Karin Hochrainer et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

NF- B, the first quarter-century: remarkable progress and outstanding questions

(2012) M. S. Hayden et al.   GENES & DEVELOPMENT

MDM2 (murine double minute-2) links inflammation and tubular cell healing during acute kidney injury in mice

(2012) Shrikant R. Mulay et al.   KIDNEY INTERNATIONAL

p53-mediated induction of Noxa and p53AIP1 requires NFκB

(2011) Jim O’Prey et al.   CELL CYCLE

The phenotype of MDM2 auto-degradation after DNA damage is due to epitope masking by phosphorylation

(2011) Qian Cheng et al.   CELL CYCLE

Crosstalk between MYCN and MDM2-p53 signal pathways regulates tumor cell growth and apoptosis in neuroblastoma

(2011) Jing He et al.   CELL CYCLE

Hierarchies of NF-κB target-gene regulation

(2011) Stephen T Smale   NATURE IMMUNOLOGY

Return to homeostasis: downregulation of NF-κB responses

(2011) Jürgen Ruland   NATURE IMMUNOLOGY

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

Inflammation meets cancer, with NF-κB as the matchmaker

(2011) Yinon Ben-Neriah et al.   NATURE IMMUNOLOGY

Suppressor of cytokine signaling 1 (SOCS1) limits NFκB signaling by decreasing p65 stability within the cell nucleus

(2010) Julia Strebovsky et al.   FASEB JOURNAL

The p53 orchestra: Mdm2 and Mdmx set the tone

(2010) Mark Wade et al.   TRENDS IN CELL BIOLOGY

Cytoplasmic tethering is involved in synergistic inhibition of p53 by Mdmx and Mdm2

(2009) Chihiro Ohtsubo et al.   CANCER SCIENCE

Pim-1 controls NF-κB signalling by stabilizing RelA/p65

(2009) K Nihira et al.   CELL DEATH AND DIFFERENTIATION

Phosphorylation of p53 by IκB kinase 2 promotes its degradation by β-TrCP

(2009) Yifeng Xia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activated p53 induces NF-κB DNA binding but suppresses its transcriptional activation

(2008) Keiko Kawauchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS