Interaction between p53 and estradiol pathways in transcriptional responses to chemotherapeutics

Network Modeling of MDM2 Inhibitor-Oxaliplatin Combination Reveals Biological Synergy in wt-p53 solid tumors

(2015) Asfar S. Azmi et al.   Oncotarget

Metformin targets Stat3 to inhibit cell growth and induce apoptosis in triple-negative breast cancers

(2012) Xin-Sheng Deng et al.   CELL CYCLE

SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response

(2012) Andreas Mund et al.   NUCLEIC ACIDS RESEARCH

Estrogen receptor prevents p53-dependent apoptosis in breast cancer

(2012) S. T. Bailey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of Toll-like Receptor 5 on Breast Cancer Cells by Flagellin Suppresses Cell Proliferation and Tumor Growth

(2011) Z. Cai et al.   CANCER RESEARCH

RB1 and p53 at the crossroad of EMT and triple-negative breast cancer

(2011) Zhe Jiang et al.   CELL CYCLE

Cortical localization of APC2 plays a role in actin organization but not in Wnt signaling in Drosophila

(2011) M.-N. Zhou et al.   JOURNAL OF CELL SCIENCE

Expanding the Paradigm for Estrogen Receptor Binding and Transcriptional Activation

(2011) S. R. Joshi et al.   MOLECULAR ENDOCRINOLOGY

RSAT 2011: regulatory sequence analysis tools

(2011) M. Thomas-Chollier et al.   NUCLEIC ACIDS RESEARCH

Epha2 is a critical oncogene in melanoma

(2011) D Udayakumar et al.   ONCOGENE

The Toll-Like Receptor Gene Family Is Integrated into Human DNA Damage and p53 Networks

(2011) Daniel Menendez et al.   PLoS Genetics

Estrogen levels act as a rheostat on p53 levels and modulate p53-dependent responses in breast cancer cell lines

(2010) Lynnette Fernández-Cuesta et al.   BREAST CANCER RESEARCH AND TREATMENT

p53-family proteins and their regulators: hubs and spokes in tumor suppression

(2010) L Collavin et al.   CELL DEATH AND DIFFERENTIATION

Regulation of IGF2 transcript and protein expression by altered methylation in breast cancer

(2010) Preetha J. Shetty et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Towards a knowledge-based Human Protein Atlas

(2010) Mathias Uhlen et al.   NATURE BIOTECHNOLOGY

Translating p53 into the clinic

(2010) Chit Fang Cheok et al.   Nature Reviews Clinical Oncology

The C terminus of p53 binds the N-terminal domain of MDM2

(2010) Masha V Poyurovsky et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Intermediate filament dynamics and breast cancer: Aberrant promoter methylation of the Synemin gene is associated with early tumor relapse

(2010) E Noetzel et al.   ONCOGENE

The Coordinated P53 and Estrogen Receptor Cis-Regulation at an FLT1 Promoter SNP Is Specific to Genotoxic Stress and Estrogenic Compound

(2010) Yari Ciribilli et al.   PLoS One

Mechanisms of estrogen receptor antagonism toward p53 and its implications in breast cancer therapeutic response and stem cell regulation

(2010) S. D. Konduri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences

(2010) D. Menendez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of transcription factor selectivity

(2010) Yongping Pan et al.   TRENDS IN GENETICS

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Estradiol in Breast Cancer Treatment

(2009) Pamela N. Munster et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

STITCH 2: an interaction network database for small molecules and proteins

(2009) Michael Kuhn et al.   NUCLEIC ACIDS RESEARCH

Disruption of estrogen receptor α-p53 interaction in breast tumors: a novel mechanism underlying the anti-tumor effect of radiation therapy

(2008) Wensheng Liu et al.   BREAST CANCER RESEARCH AND TREATMENT

EphA2 Is an Essential Mediator of UV Radiation-Induced Apoptosis

(2008) G. Zhang et al.   CANCER RESEARCH

Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

(2008) P. A.C. Cloos et al.   GENES & DEVELOPMENT

p53-Targeted LSD1 Functions in Repression of Chromatin Structure and Transcription In Vivo

(2008) W.-W. Tsai et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanisms of regulatory diversity within the p53 transcriptional network

(2008) J M Espinosa   ONCOGENE