The PTEN-Akt pathway impacts the integrity and composition of mitotic centrosomes

Akt Inhibitor A-443654 Interferes with Mitotic Progression by Regulating Aurora A Kinase Expression

(2015) Xuesong Liu et al.   NEOPLASIA

Polo-like kinase 1 directs the AMPK-mediated activation of myosin regulatory light chain at the cytokinetic cleavage furrow independently of energy balance

(2012) Alejandro Vazquez-Martin et al.   CELL CYCLE

4E-BP1 participates in maintaining spindle integrity and genomic stability via interacting with PLK1

(2012) Zeng-Fu Shang et al.   CELL CYCLE

Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cγ at the centrosome

(2012) Hélène Lelièvre et al.   Molecular Cancer

Subdiffraction imaging of centrosomes reveals higher-order organizational features of pericentriolar material

(2012) Steffen Lawo et al.   NATURE CELL BIOLOGY

The Role of γ-Tubulin in Centrosomal Microtubule Organization

(2012) Eileen O'Toole et al.   PLoS One

PTEN Protein Phosphatase Activity Correlates with Control of Gene Expression and Invasion, a Tumor-Suppressing Phenotype, But Not with AKT Activity

(2012) P. Tibarewal et al.   Science Signaling

Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent Manner

(2011) Min Sup Song et al.   CELL

Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair

(2011) Arun Gupta et al.   CELL CYCLE

Polo-like kinase 1 regulates activation of AMP-activated protein kinase (AMPK) at the mitotic apparatus

(2011) Alejandro Vazquez-Martin et al.   CELL CYCLE

ΔNp63α regulates keratinocyte proliferation by controlling PTEN expression and localization

(2011) M K Leonard et al.   CELL DEATH AND DIFFERENTIATION

PLK1 phosphorylation of pericentrin initiates centrosome maturation at the onset of mitosis

(2011) Kwanwoo Lee et al.   JOURNAL OF CELL BIOLOGY

The PI3K–Akt mediates oncogenic Met-induced centrosome amplification and chromosome instability

(2010) Hyun-Ja Nam et al.   CARCINOGENESIS

Akt inhibitors in clinical development for the treatment of cancer

(2010) Sumanta Kumar Pal et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

The PTEN Phosphatase Controls Intestinal Epithelial Cell Polarity and Barrier Function: Role in Colorectal Cancer Progression

(2010) Marie-Josée Langlois et al.   PLoS One

Enhanced genomic instabilities caused by deregulated microtubule dynamics and chromosome segregation: a perspective from genetic studies in mice

(2009) C. V. Rao et al.   CARCINOGENESIS

Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN

(2009) L Davidson et al.   ONCOGENE

Plk1-Dependent Recruitment of γ-Tubulin Complexes to Mitotic Centrosomes Involves Multiple PCM Components

(2009) Laurence Haren et al.   PLoS One

EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors

(2008) Li Li et al.   NEURO-ONCOLOGY