Aurora A is differentially expressed in gliomas, is associated with patient survival in glioblastoma and is a potential chemotherapeutic target in gliomas

p300- and Myc-mediated regulation of glioblastoma multiforme cell differentiation

(2015)   Oncotarget

Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes

(2015)   Oncotarget

The NFκB pathway: a therapeutic target in glioblastoma

(2015) Lorena Nogueira et al.   Oncotarget

Aurora inhibitor MLN8237 in combination with docetaxel enhances apoptosis and anti-tumor activity in mantle cell lymphoma

(2011) Wenqing Qi et al.   BIOCHEMICAL PHARMACOLOGY

Efficacy and pharmacokinetic/pharmacodynamic evaluation of the Aurora kinase A inhibitor MLN8237 against preclinical models of pediatric cancer

(2011) Hernan Carol et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state

(2010) J. den Hollander et al.   BLOOD

A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma

(2010) G. Gorgun et al.   BLOOD

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Suppression of Aurora-A oncogenic potential by c-Myc downregulation

(2010) Shangbin Yang et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

The novel Aurora A kinase inhibitor MLN8237 is active in resistant chronic myeloid leukaemia and significantly increases the efficacy of nilotinib

(2010) Kevin R. Kelly et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Aurora kinase A as a rational target for therapy in glioblastoma

(2010) Valerie N. Barton et al.   Journal of Neurosurgery-Pediatrics

MLN8054, an Inhibitor of Aurora A Kinase, Induces Senescence in Human Tumor Cells Both In vitro and In vivo

(2010) J. J. Huck et al.   MOLECULAR CANCER RESEARCH

Phase I Study of the Selective Aurora A Kinase Inhibitor MLN8054 in Patients with Advanced Solid Tumors: Safety, Pharmacokinetics, and Pharmacodynamics

(2010) T. Macarulla et al.   MOLECULAR CANCER THERAPEUTICS

The Proneural Molecular Signature Is Enriched in Oligodendrogliomas and Predicts Improved Survival among Diffuse Gliomas

(2010) Lee A. D. Cooper et al.   PLoS One

Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myeloma

(2009) D. Hose et al.   BLOOD

Stabilization of N-Myc Is a Critical Function of Aurora A in Human Neuroblastoma

(2009) Tobias Otto et al.   CANCER CELL

Aurora A Regulates Prometaphase Progression by Inhibiting the Ability of RASSF1A to Suppress APC-Cdc20 Activity

(2009) S. J. Song et al.   CANCER RESEARCH

Aurora kinase inhibitors in preclinical and clinical testing

(2009) Chun Hei Antonio Cheung et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Retracted: Overexpression of Aurora A by loss of CHFR gene expression increases the growth and survival of HTLV-1-infected T cells through enhanced NF-κB activity

(2009) Mariko Tomita et al.   INTERNATIONAL JOURNAL OF CANCER

Aurora-A Overexpression in Mouse Liver Causes p53-Dependent Premitotic Arrest during Liver Regeneration

(2009) C.-C. Li et al.   MOLECULAR CANCER RESEARCH

Rembrandt: Helping Personalized Medicine Become a Reality through Integrative Translational Research

(2009) S. Madhavan et al.   MOLECULAR CANCER RESEARCH

Aurora A is a negative prognostic factor and a new therapeutic target in human neuroblastoma

(2009) X. Shang et al.   MOLECULAR CANCER THERAPEUTICS

The Aurora kinase inhibitor SNS-314 shows broad therapeutic potential with chemotherapeutics and synergy with microtubule-targeted agents in a colon carcinoma model

(2009) E. C. VanderPorten et al.   MOLECULAR CANCER THERAPEUTICS

Comparative immunohistochemical analysis of aurora-A and aurora-B expression in human glioblastomas. Associations with proliferative activity and clinicopathological features

(2009) Vassilis Samaras et al.   PATHOLOGY RESEARCH AND PRACTICE

Polo-Like Kinase-1 Controls Aurora A Destruction by Activating APC/C-Cdh1

(2009) Renske van Leuken et al.   PLoS One

Aurora-A interacts with Cyclin B1 and enhances its stability

(2008) Lili Qin et al.   CANCER LETTERS

Identification of Aurora-A as a Direct Target of E2F3 during G2/M Cell Cycle Progression

(2008) Lili He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aurora A Is Essential for Early Embryonic Development and Tumor Suppression

(2008) Lin-Yu Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional Regulation of Serine/Threonine Kinase-15 (STK15) Expression by Hypoxia and HIF-1

(2008) Alexandra Klein et al.   MOLECULAR BIOLOGY OF THE CELL

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Fbw7 regulates the activity of endoreduplication mediators and the p53 pathway to prevent drug-induced polyploidy

(2008) S Finkin et al.   ONCOGENE

Aurora A overexpression induces cellular senescence in mammary gland hyperplastic tumors developed in p53-deficient mice

(2008) D Zhang et al.   ONCOGENE

The aurora kinase A regulates GSK-3β in gastric cancer cells

(2008) A A Dar et al.   ONCOGENE

Pdx-1-Driven Overexpression of Aurora A Kinase Induces Mild Ductal Dysplasia of Pancreatic Ducts Near Islets in Transgenic Mice

(2008) Steven L. Warner et al.   PANCREAS

Bora and the Kinase Aurora A Cooperatively Activate the Kinase Plk1 and Control Mitotic Entry

(2008) A. Seki et al.   SCIENCE