Discordance between phosphorylation and recruitment of 53BP1 in response to DNA double-strand breaks

Pseudo-DNA damage response in senescent cells

(2011) Tatyana V. Pospelova et al.   CELL CYCLE

MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks

(2011) Michael Fraser et al.   CELL CYCLE

Regulation of DNA End Joining, Resection, and Immunoglobulin Class Switch Recombination by 53BP1

(2011) Anne Bothmer et al.   MOLECULAR CELL

Protein-Protein Interactions Occur Between p53 Phosphoforms and ATM and 53BP1 at Sites of Exogenous DNA Damage

(2011) Shahnaz T. Al Rashid et al.   RADIATION RESEARCH

ATM-dependent phosphorylation of 53BP1 in response to genomic stress in oxic and hypoxic cells

(2011) Shane M. Harding et al.   RADIOTHERAPY AND ONCOLOGY

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

(2010) Samuel F. Bunting et al.   CELL

Solving the RIDDLE of 53BP1 recruitment to sites of damage

(2010) Grant S. Stewart   CELL CYCLE

DNA damage foci in mitosis are devoid of 53BP1

(2010) Glyn Nelson et al.   CELL CYCLE

Dephosphorylation of γ-H2AX by WIP1: An important homeostatic regulatory event in DNA repair and cell cycle control

(2010) Sung-Hwan Moon et al.   CELL CYCLE

The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks

(2010) Asako J. Nakamura et al.   CELL CYCLE

A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation

(2010) Tracey A. Dobbs et al.   DNA REPAIR

The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax

(2010) Aaron A. Goodarzi et al.   DNA REPAIR

Simultaneous electrophoretic analysis of proteins of very high and low molecular mass using Tris-acetate polyacrylamide gels

(2010) Monica Cubillos-Rojas et al.   ELECTROPHORESIS

DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion

(2010) F. Rodier et al.   JOURNAL OF CELL SCIENCE

Role of ATM and the Damage Response Mediator Proteins 53BP1 and MDC1 in the Maintenance of G2/M Checkpoint Arrest

(2010) A. Shibata et al.   MOLECULAR AND CELLULAR BIOLOGY

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

(2010) Eva Petermann et al.   MOLECULAR CELL

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

(2010) Peter Bouwman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Transient ATM Kinase Inhibition Disrupts DNA Damage-Induced Sister Chromatid Exchange

(2010) J. S. White et al.   Science Signaling

The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

(2009) Grant S. Stewart et al.   CELL

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2

(2009) Andrea Beucher et al.   EMBO JOURNAL

Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells

(2009) Nozomi Tomimatsu et al.   EMBO REPORTS

Protein Phosphatase 5 Regulates the Function of 53BP1 after Neocarzinostatin-induced DNA Damage

(2009) Yoonsung Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essential Role for DNA-PKcs in DNA Double-Strand Break Repair and Apoptosis in ATM-Deficient Lymphocytes

(2009) Elsa Callén et al.   MOLECULAR CELL

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols

ATM Activation and Signaling under Hypoxic Conditions

(2008) Z. Bencokova et al.   MOLECULAR AND CELLULAR BIOLOGY

DNA Damage Responses: Mechanisms and Roles in Human Disease: 2007 G.H.A. Clowes Memorial Award Lecture

(2008) M. B. Kastan   MOLECULAR CANCER RESEARCH

ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin

(2008) Aaron A. Goodarzi et al.   MOLECULAR CELL

53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

(2008) Nadya Dimitrova et al.   NATURE