From oncogene to tumor suppressor

Dynamics of epigenetic modifications in leukemia

(2011) I. Uribesalgo et al.   Briefings in Functional Genomics

Actomyosin-Mediated Cellular Tension Drives Increased Tissue Stiffness and β-Catenin Activation to Induce Epidermal Hyperplasia and Tumor Growth

(2011) Michael S. Samuel et al.   CANCER CELL

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

Myc’s secret life without Max

(2011) Peter Gallant et al.   CELL CYCLE

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

(2011) Johannes Zuber et al.   NATURE

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

(2011) Mark A. Dawson et al.   NATURE

E-box-independent regulation of transcription and differentiation by MYC

(2011) Iris Uribesalgo et al.   NATURE CELL BIOLOGY

The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis

(2011) Elisabete M. Nascimento et al.   NATURE CELL BIOLOGY

Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts

(2011) D Perna et al.   ONCOGENE

Shape-Induced Terminal Differentiation of Human Epidermal Stem Cells Requires p38 and Is Regulated by Histone Acetylation

(2011) John T. Connelly et al.   PLoS One

Targeting MYC dependence in cancer by inhibiting BET bromodomains

(2011) J. A. Mertz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myc-Nick: A Cytoplasmic Cleavage Product of Myc that Promotes α-Tubulin Acetylation and Cell Differentiation

(2010) Maralice Conacci-Sorrell et al.   CELL

Inhibition of cell differentiation: A critical mechanism for MYC-mediated carcinogenesis?

(2010) Javier Leon et al.   CELL CYCLE

The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy

(2010) Lars-Gunnar Larsson et al.   EXPERIMENTAL CELL RESEARCH

Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions

(2010) John T. Connelly et al.   NATURE CELL BIOLOGY

Differentiation therapy of leukemia: 3 decades of development

(2009) D. Nowak et al.   BLOOD

Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis

(2009) Kim B. Jensen et al.   Cell Stem Cell

Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells

(2009) Gao-Hui Zhu et al.   DIFFERENTIATION

JAK2 phosphorylates histone H3Y41 and excludes HP1α from chromatin

(2009) Mark A. Dawson et al.   NATURE

Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis

(2009) Souhila Medjkane et al.   NATURE CELL BIOLOGY

Myc-Mediated Transcriptional Repression by Recruitment of Histone Deacetylase

(2008) J. F. Kurland et al.   CANCER RESEARCH

Modelling Myc inhibition as a cancer therapy

(2008) Laura Soucek et al.   NATURE

Max-independent functions of Myc in Drosophila melanogaster

(2008) Dominik Steiger et al.   NATURE GENETICS

A positive role for Myc in TGFβ-induced Snail transcription and epithelial-to-mesenchymal transition

(2008) A P Smith et al.   ONCOGENE