Combined inhibition of Wee1 and Hsp90 activates intrinsic apoptosis in cancer cells

Proteotoxic stress targeted therapy (PSTT): induction of protein misfolding enhances the antitumor effect of the proteasome inhibitor bortezomib

(2015) Nickolay Neznanov et al.   Oncotarget

Casein kinase 2 phosphorylation of Hsp90 threonine 22 modulates chaperone function and drug sensitivity

(2015) Mehdi Mollapour et al.   Oncotarget

Chaperones and the maturation of steroid hormone receptor complexes

(2015) Yizhi Jane Tao et al.   Oncotarget

Hsp90 Molecular Chaperone Inhibitors: Are We There Yet?

(2012) L. Neckers et al.   CLINICAL CANCER RESEARCH

Survivin Signaling in Clinical Oncology: A Multifaceted Dragon

(2012) Jagat R. Kanwar et al.   MEDICINAL RESEARCH REVIEWS

Survivin Is a Therapeutic Target in Merkel Cell Carcinoma

(2012) R. Arora et al.   Science Translational Medicine

Survivin in Solid Tumors: Rationale for Development of Inhibitors

(2012) David N. Church et al.   Current Oncology Reports

Endogenous Angiogenesis Inhibitor Blocks Tumor Growth via Direct and Indirect Effects on Tumor Microenvironment

(2011) Dimitra Bourboulia et al.   AMERICAN JOURNAL OF PATHOLOGY

Antiangiogenic therapy using nanotechnological-based delivery system

(2011) Jagat R. Kanwar et al.   DRUG DISCOVERY TODAY

WEE1 Inhibition Sensitizes Basal Breast Cancer Cells to TRAIL-Induced Apoptosis

(2011) S. V. Garimella et al.   MOLECULAR CANCER RESEARCH

MK1775, a Selective Wee1 Inhibitor, Shows Single-Agent Antitumor Activity against Sarcoma Cells

(2011) J. M. Kreahling et al.   MOLECULAR CANCER THERAPEUTICS

MK-1775, a small molecule Wee1 inhibitor, enhances anti-tumor efficacy of various DNA-damaging agents, including 5-fluorouracil

(2010) Hiroshi Hirai et al.   CANCER BIOLOGY & THERAPY

Survivin as a global  target of intrinsic tumor suppression networks

(2010) Minakshi Guha et al.   CELL CYCLE

Hsp90 phosphorylation, Wee1 and the cell cycle

(2010) Mehdi Mollapour et al.   CELL CYCLE

Swe1Wee1-Dependent Tyrosine Phosphorylation of Hsp90 Regulates Distinct Facets of Chaperone Function

(2010) Mehdi Mollapour et al.   MOLECULAR CELL

Identification of WEE1 as a potential molecular target in cancer cells by RNAi screening of the human tyrosine kinome

(2009) Lyndsay M. Murrow et al.   BREAST CANCER RESEARCH AND TREATMENT

Survivin: Key Regulator of Mitosis and Apoptosis and Novel Target for Cancer Therapeutics

(2008) A. C. Mita et al.   CLINICAL CANCER RESEARCH

Epidermal growth factor receptor expression analysis in chemotherapy-naive patients with advanced non-small-cell lung cancer treated with gefitinib or placebo in combination with platinum-based chemotherapy

(2008) Giuseppe Giaccone et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone

(2008) A. Yano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA