p53 reactivation

Allele-Specific p53 Mutant Reactivation

(2012) Xin Yu et al.   CANCER CELL

PRIMA-1Met/APR-246 induces wild-type p53-dependent suppression of malignant melanoma tumor growth in 3D culture and in vivo

(2011) Wenjie Bao et al.   CELL CYCLE

Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs

(2011) Rosa Puca et al.   CELL CYCLE

Zinc supplementation augments in vivo antitumor effect of chemotherapy by restoring p53 function

(2011) Ofer Margalit et al.   INTERNATIONAL JOURNAL OF CANCER

Rescue of the apoptotic-inducing function of mutant p53 by small molecule RITA

(2010) Carolyn Y. Zhao et al.   CELL CYCLE

The missing Zinc: p53 misfolding and cancer

(2010) Stewart N. Loh   Metallomics

Reversible Dysfunction of Wild-Type p53 following Homeodomain-Interacting Protein Kinase-2 Knockdown

(2008) R. Puca et al.   CANCER RESEARCH

Restoring wtp53 activity in HIPK2 depleted MCF7 cells by modulating metallothionein and zinc

(2008) Rosa Puca et al.   EXPERIMENTAL CELL RESEARCH