The real face of HIF1α in the tumor process

STAT3, HIF-1, glucose addiction and Warburg effect

(2016) James E. Darnell   Aging-US

A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction

(2016) Marco Demaria et al.   Aging-US

HIF-1α antagonizes p53-mediated apoptosis by triggering HIPK2 degradation

(2016) Lavinia Nardinocchi et al.   Aging-US

Regulation of life span by mitochondrial respiration: the HIF-1 and ROS connection

(2016) Ara B. Hwang et al.   Aging-US

Targeted cellular metabolism for cancer chemotherapy with recombinant arginine-degrading enzymes

(2015)   Oncotarget

Pyruvate kinase M2 regulates glucose metabolism by functioning as a coactivator for hypoxia-inducible factor 1 in cancer cells

(2015) Weibo Luo et al.   Oncotarget

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

The purpose of the HIF-1/PHD feedback loop: To limit mTOR-induced HIF-1α

(2011) Zoya N. Demidenko et al.   CELL CYCLE

In vivo pH in metabolic-defective Ras-transformed fibroblast tumors: Key role of the monocarboxylate transporter, MCT4, for inducing an alkaline intracellular pH

(2011) Johanna Chiche et al.   INTERNATIONAL JOURNAL OF CANCER

Therapeutic targeting of cancer cell metabolism

(2011) Chi V. Dang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Oxygen Sensing, Homeostasis, and Disease

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Rethinking the Warburg Effect with Myc Micromanaging Glutamine Metabolism

(2010) C. V. Dang   CANCER RESEARCH

Nitrogen anabolism underlies the importance of glutaminolysis in proliferating cells

(2010) Meng Meng et al.   CELL CYCLE

HIF1-alpha functions as a tumor promoter in cancer-associated fibroblasts, and as a tumor suppressor in breast cancer cells

(2010) Barbara Chiavarina et al.   CELL CYCLE

Glutaminolysis: Supplying carbon or nitrogen or both for cancer cells?

(2010) Chi V. Dang   CELL CYCLE

Hypoxia and energetic tumour metabolism

(2010) M Christiane Brahimi-Horn et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells

(2010) Katarína Smolková et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer

(2010) Johanna Chiche et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Insulin promotes proliferative vitality and invasive capability of pancreatic cancer cells via hypoxia-inducible factor 1α pathway

(2010) Li Wang et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

MYC-Induced Cancer Cell Energy Metabolism and Therapeutic Opportunities

(2009) C. V. Dang et al.   CLINICAL CANCER RESEARCH

HIF-1: upstream and downstream of cancer metabolism

(2009) Gregg L Semenza   CURRENT OPINION IN GENETICS & DEVELOPMENT

Gene regulation in response to graded hypoxia: The non-redundant roles of the oxygen sensors and FIH in the HIF pathway

(2009) Frédéric Dayan et al.   JOURNAL OF THEORETICAL BIOLOGY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

(2008) Huafeng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression

(2008) Jennifer S. Fang et al.   SEMINARS IN CANCER BIOLOGY