Putting the brakes on p53-driven apoptosis

The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway

(2016) Lioubov G. Korotchkina et al.   Aging-US

Direct interaction between p53 and Tid1 proteins affects p53 mitochondrial localization and apoptosisy as a Target for Cancer Therapy?

(2015)   Oncotarget

DNA-PKCS binding to p53 on the p21WAF1/CIP1 promoter blocks transcription resulting in cell death

(2015) Richard Hill et al.   Oncotarget

AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis

(2012) Katja Höpker et al.   EMBO JOURNAL

The p53 network: cellular and systemic DNA damage responses in aging and cancer

(2012) H. Christian Reinhardt et al.   TRENDS IN GENETICS

Exploiting synthetic lethal interactions for targeted cancer therapy

(2011) H. Christian Reinhardt et al.   CELL CYCLE

Outcome of the p53-mediated DNA damage response in neuroblastoma is determined by morphological subtype and MYCN expression

(2011) Jane Carr-Wilkinson et al.   CELL CYCLE

The relative contribution of pro-apoptotic p53-target genes in the triggering of apoptosis following DNA damage in vitro and in vivo

(2011) Kageaki Kuribayashi et al.   CELL CYCLE

Poly(ADP-ribose) polymerase inhibition enhances p53-dependent and -independent DNA damage responses induced by DNA damaging agent

(2011) Diana Nguyen et al.   CELL CYCLE

Is post-transcriptional stabilization, splicing and translation of selective mRNAs a key to the DNA damage response?

(2011) H. Christian Reinhardt et al.   CELL CYCLE

Cellular quiescence caused by the Mdm2 inhibitor Nutlin-3A

(2010) Lioubov G. Korotchkina et al.   CELL CYCLE

p53: The pivot between cell cycle arrest and senescence

(2010) Raffaela Santoro et al.   CELL CYCLE

Weak p53 permits senescence during cell cycle arrest

(2010) Olga V. Leontieva et al.   CELL CYCLE

Regulation of p53 activity by HIPK2: molecular mechanisms and therapeutical implications in human cancer cells

(2010) R Puca et al.   ONCOGENE

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2

(2009) H Christian Reinhardt et al.   CURRENT OPINION IN CELL BIOLOGY

The combined status of ATM and p53 link tumor development with therapeutic response

(2009) H. Jiang et al.   GENES & DEVELOPMENT

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Mechanisms of regulatory diversity within the p53 transcriptional network

(2008) J M Espinosa   ONCOGENE