Flavopiridol induces phosphorylation of AKT in a human glioblastoma cell line, in contrast to siRNA-mediated silencing of Cdk9: Implications for drug design and development

The Phosphatidylinositol 3-kinase/AKT/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients

(2015)   Oncotarget

Therapeutic Strategies to Target Multiple Kinases in Glioblastoma

(2012) Sith Sathornsumetee   Anti-Cancer Agents in Medicinal Chemistry

ASPM and microcephalin expression in epithelial ovarian cancer correlates with tumour grade and survival

(2011) A Brüning-Richardson et al.   BRITISH JOURNAL OF CANCER

A role for cdk9-cyclin k in maintaining genome integrity

(2011) David S. Yu et al.   CELL CYCLE

MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks

(2011) Michael Fraser et al.   CELL CYCLE

Dynamics of cancer cell subpopulations in primary and metastatic colorectal tumors

(2011) Teodora Evgenieva Goranova et al.   CLINICAL & EXPERIMENTAL METASTASIS

A history of TFIIH: Two decades of molecular biology on a pivotal transcription/repair factor

(2011) Jean-Marc Egly et al.   DNA REPAIR

Heterogeneity of anticancer drug sensitivity in squamous cell carcinoma of the tongue

(2011) Minako Suzuki et al.   Human Cell

Role of the cyclin-dependent kinase 9-related pathway in mammalian gene expression and human diseases

(2010) Gaetano Romano et al.   CELL CYCLE

CYCLINg through transcription: Post-translational modifications of P-TEFb regulate transcription elongation

(2010) Sungyoo Cho et al.   CELL CYCLE

Cyclin T1 overexpression induces malignant transformation and tumor growth

(2010) Cristian Moiola et al.   CELL CYCLE

Cyclin-Dependent Kinase Inhibitors as Anticancer Drugs

(2010) Vladimir Krystof et al.   CURRENT DRUG TARGETS

Cell death induction in resting lymphocytes by pan-Cdk inhibitor, but not by Cdk4/6 selective inhibitor

(2010) Makiko Kobayashi et al.   INVESTIGATIONAL NEW DRUGS

8-Amino-Adenosine Inhibits Multiple Mechanisms of Transcription

(2010) J. A. Frey et al.   MOLECULAR CANCER THERAPEUTICS

Mechanism of action of SNS-032, a novel cyclin-dependent kinase inhibitor, in chronic lymphocytic leukemia

(2009) Rong Chen et al.   BLOOD

Akt is activated in chronic lymphocytic leukemia cells and delivers a pro-survival signal: the therapeutic potential of Akt inhibition

(2009) J. Zhuang et al.   HAEMATOLOGICA

Binding to DNA of the RNA-polymerase II C-terminal domain allows discrimination between Cdk7 and Cdk9 phosphorylation

(2009) G. Lolli   NUCLEIC ACIDS RESEARCH

Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells

(2009) Hui-Fang Li et al.   Radiation Oncology

Making a neuron: Cdk5 in embryonic and adult neurogenesis

(2009) Sebastian Jessberger et al.   TRENDS IN NEUROSCIENCES

Roscovitine Reduces Neuronal Loss, Glial Activation, and Neurologic Deficits after Brain Trauma

(2008) Genell D Hilton et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Dopaminergic and Glutamatergic Signaling Crosstalk in Huntington's Disease Neurodegeneration: The Role of p25/Cyclin-Dependent Kinase 5

(2008) P. Paoletti et al.   JOURNAL OF NEUROSCIENCE

Role of cdk9 in the Optimization of Expression of the Genes Regulated by ICP22 of Herpes Simplex Virus 1

(2008) L. O. Durand et al.   JOURNAL OF VIROLOGY

CDK9 a Potential Target for Drug Development

(2008) Fernanda Canduri et al.   Medicinal Chemistry

CDK inhibitors in cancer therapy: what is next?

(2007) Marcos Malumbres et al.   TRENDS IN PHARMACOLOGICAL SCIENCES