Article
Veterinary Sciences
Adriana Gyorke, Mirabela Oana Dumitrache, Aurora Livia Ursache, Gianluca D'Amico, Viorica Mircean
Summary: This article describes two cases of notoedric mange concurrent with aelurostrongylidosis in two domestic-owned cats from a rural environment in Romania. The cats were successfully treated with selamectin spot-on formulation and improving the quality of their lives was crucial for the success of the treatment.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Multidisciplinary Sciences
Matthew Chun, Robert Clarke, Tingting Zhu, David Clifton, Derrick Bennett, Yiping Chen, Yu Guo, Pei Pei, Jun Lv, Canqing Yu, Ling Yang, Liming Li, Zhengming Chen, Benjamin J. Cairns
Summary: The study found that the risk estimates of stroke for individuals increase annually, with different annual increase rates for men and women, and using machine learning methods to integrate longitudinal data has value for stroke prediction.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Sabrine Marangoni, Julia Beatty, Paulo V. Steagall
Summary: A study aimed to create and validate an ethogram of acute pain behaviors in cats, including twenty-four behaviors like sitting in the back of cage, feigned sleep, and not paying attention to surroundings. This detailed ethogram can help describe and differentiate acute pain behaviors in cats effectively.
Article
Multidisciplinary Sciences
Martina Naceradska, Sona Pekova, Patrizia Danesi, Tommaso Furlanello, Roberta Calleo, Patricia Martin, Fumio Ike, Richard Malik
Summary: The study identified a novel Filobacterium sp. (F. felis) as a potential pathogen associated with feline bronchial disease, present in the lower respiratory microbiome of some cats and capable of causing chronic neutrophilic bronchitis. The research also found that Filobacterium sp. could sometimes become the predominant bacterial species in cats with lower respiratory disease.
Article
Microbiology
Ettore Napoli, Michela Pugliese, Angelo Basile, Annamaria Passantino, Emanuele Brianti
Summary: This study aimed to investigate the association between A. abstrusus infection and pulmonary hypertension (PH) and to evaluate the correlation between the number of expelled larvae and clinical, echocardiographic, and radiological alterations. The results showed that most cats exhibited pathological patterns on thoracic radiograms, but no significant echocardiographic findings of PH were detected. The number of expelled larvae was not correlated with the severity of clinical signs, but significant correlations were observed with activated partial thromboplastin time (aPTT), radiographic alterations, and ultrasonographic findings (RIVIDs).
Letter
Medicine, General & Internal
[Anonymous]
Summary: The use of aspirin for thromboprophylaxis after hip and knee replacement surgery is still debated, and limited data is available on its use in patients with extremity fractures.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Surgery
Yongyan Zhang, Ying Li, Feng Ji, Keqin Zhang, Yi Lou, Hua Xu
Summary: This study compared the effects of transcutaneous electrical acupoint stimulation and dexamethasone in preventing post-operative nausea and/or vomiting in breast surgery patients. The results showed that within 24 hours after surgery, transcutaneous electrical acupoint stimulation was not inferior to dexamethasone in preventing nausea and/or vomiting, and had higher patient satisfaction scores.
Editorial Material
Hematology
Anna Falanga, Cinzia Giaccherini
Summary: In this study, the PRISM score was developed as a new risk prediction model for venous thromboembolism prevention in outpatients with multiple myeloma. The abnormal metaphase cytogenetics was identified as a new disease-related risk factor, which contributes to the understanding and treatment of patients with multiple myeloma.
Article
Gastroenterology & Hepatology
Sally Tran, Donghak Jeong, Linda Henry, Ramsey C. Cheung, Mindie H. Nguyen
Summary: This study found poor adherence to recommended initial evaluation and long-term monitoring in patients with CHB infection, with specialist visits being a predictor of adherence. Further efforts are needed to identify barriers and improve access to care for these patients.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Multidisciplinary Sciences
Syed Waseem Abbas Sherazi, Jang-Whan Bae, Jong Yun Lee
Summary: This paper proposes a soft voting ensemble classifier (SVE) using machine learning algorithms for early prediction and diagnosis of major adverse cardiovascular events (MACE). The SVE outperformed other machine learning models in terms of accuracy and area under the ROC curve (AUC).
Article
Medicine, General & Internal
Dong-Yi Chen, Chi-Nan Tseng, Ming-Jer Hsieh, Wen-Ching Lan, Cheng-Keng Chuang, See-Tong Pang, Shao-Wei Chen, Tien-Hsing Chen, Shang-Hung Chang, I-Chang Hsieh, Pao-Hsien Chu, Ming-Shien Wen, Jen-Shi Chen, John Wen-Cheng Chang, Lai-Chu See, Wen-Kuan Huang
Summary: This study showed that among Asian patients with cancer-associated VTE, the use of NOAC was associated with a similar risk of recurrent VTE or major bleeding compared to LMWH enoxaparin, but NOAC was significantly associated with a lower rate of gastrointestinal bleeding. Further prospective studies are needed to confirm these findings.
Article
Multidisciplinary Sciences
Fahmi Al-Ashwal, Syed Azhar Syed Sulaiman, Siti Maisharah Sheikh Ghadzi, Mohammed Abdullah Kubas, Abdulsalam Halboup
Summary: A recent study assessed physicians' knowledge, attitude, and practices regarding atherosclerotic cardiovascular diseases risk assessment, finding suboptimal knowledge and practices but a positive attitude overall. Participants with more experience, following specific guidelines, or using risk calculators had higher knowledge and practices. However, physicians seeing more patients per day had lower risk assessment and counseling practices.
Article
Multidisciplinary Sciences
Lorenzo Falsetti, Matteo Rucco, Marco Proietti, Giovanna Viticchi, Vincenzo Zaccone, Mattia Scarponi, Laura Giovenali, Gianluca Moroncini, Cinzia Nitti, Aldo Salvi
Summary: The study utilized topological data analysis and machine learning techniques to identify risk factors for therapeutic failure, stroke/TIA, and major bleeding in critically ill patients with pre-existing atrial fibrillation. Specific risk factors were identified and dedicated clinical prediction models were successfully engineered, accurately predicting clinical outcomes for these patients.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Andrea Hernandez-Bures, Jason B. Pieper, Willie A. Bidot, Miranda O'Dell, William E. Sander, Carol W. Maddox
Summary: A study in a region of Puerto Rico revealed a 19% prevalence of dermatophytosis among stray dogs and cats. Asymptomatic animals had a higher positivity rate of 36% compared to 13.5% in animals with clinical lesions. All 19 dermatophytes identified through microscopic evaluation were confirmed using MALDI-TOF MS.
Article
Obstetrics & Gynecology
Sharla Rent, Holly Brine, Maria Fernanda de Almeida, Ruth Guinsburg, Ligia Rugolo, Fabio Mosca, Daniele Trevisanuto, Gary Weiner
Summary: The testing and treatment thresholds for early-onset neonatal sepsis were derived and compared to those used in the Kaiser-Permanente (KP) Sepsis Calculator through surveys in the United States, Brazil, and Italy. The test thresholds from clinical vignettes were lower or equivalent to the KP calculator thresholds, while the treatment thresholds did not reach the 50% cutoff necessary. The test threshold used by the KP calculator was consistent with the threshold chosen by clinicians given a vignette and risk estimate, but the KP treatment threshold was lower compared to those derived using all 3 methods.
JOURNAL OF PERINATOLOGY
(2021)
Article
Entomology
Sean Farrell, John McGarry, Peter-John Mantyla Noble, Gina J. Pinchbeck, Sophie Cantwell, Alan D. Radford, David A. Singleton
Summary: A study found that flea infestation in small animals in Great Britain is associated with the animals' origin and age. Animals from less deprived areas have lower odds of flea infestation, and cases peak before 12 months of age.
MEDICAL AND VETERINARY ENTOMOLOGY
(2023)
Article
Veterinary Sciences
Lucy J. J. Norris, Gina L. L. Pinchbeck, Peter-John M. Noble, Alan D. D. Radford
Summary: This study evaluated the demographics, temporal trends, and associated factors of dogs with cropped ears visiting veterinary practices in the UK. It found that a significant proportion of the dogs with cropped ears were imported from countries where ear cropping is illegal. The study highlights the need to educate owners and veterinary surgeons about the welfare and legal implications of ear cropping.
Article
Agriculture, Dairy & Animal Science
Camilla Smoglica, Alberto Vergara, Simone Angelucci, Anna Rita Festino, Antonio Antonucci, Fulvio Marsilio, Cristina Esmeralda Di Francesco
Summary: Antibiotic resistance is a global problem involving humans, animals, and the environment. The One Health approach was used to study wild and domestic species in Maiella national park, Italy. The study found various bacterial species with resistant profiles, including resistance against important antibiotics for human medicine.
Article
Virology
Mark E. Westman, Juliana Giselbrecht, Jacqueline M. Norris, Richard Malik, Jennifer Green, Elle Burton-Bradley, Ashley Cheang, Theres Meili, Marina L. Meli, Katrin Hartmann, Regina Hofmann-Lehmann
Summary: This study evaluated the field performance of a new rapid point-of-care test kit in determining different feline leukemia virus (FeLV) infection outcomes, as well as its performance in detecting feline immunodeficiency virus (FIV) infection status. The results showed that the test kit was unable to accurately determine different FeLV infection outcomes in field samples and improvements are needed.
Article
Virology
Sandra Vreman, Elisabeth M. D. L. van der Heijden, Lars Ravesloot, Irene S. Ludwig, Judith M. A. van den Brand, Frank Harders, Andries A. Kampfraath, Herman F. Egberink, Jose L. Gonzales, Nadia Oreshkova, Femke Broere, Wim H. M. van der Poel, Nora M. Gerhards
Summary: Several reports demonstrated domestic cats' susceptibility to SARS-CoV-2 infection. In this study, the immune responses in cats after experimental inoculation were investigated, along with infection kinetics and pathological lesions. Infected cats showed mild lung changes and viral antigen expression, but no clinical signs. Viral RNA was present in nasal and throat swabs until day 7, and infectious virus could be isolated from nose, trachea, and lungs until day 7. Cats developed a humoral immune response from day 7 onwards, with limited cellular immune responses on day 7.
Article
Virology
Sandra Felten, Ute Klein-Richers, Stefan Unterer, Michele Bergmann, Yury Zablotski, Regina Hofmann-Lehmann, Katrin Hartmann
Summary: This study aimed to describe the shedding patterns of feline coronavirus (FCoV) in catteries and analyze risk factors for high-intensity shedding or non-shedding. The proportion of high-intensity shedders and non-shedding cats was higher than previously reported, possibly due to housing conditions, genetic susceptibility, or differences in the study period. Certain breeds had a higher risk of high-intensity shedding, and individual hygiene procedures may have influenced FCoV shedding frequency. Smaller group sizes were protective against FCoV shedding.
Article
Microbiology
Nora M. M. Gerhards, Jose L. L. Gonzales, Sandra Vreman, Lars Ravesloot, Judith M. A. van den Brand, Harmen P. P. Doekes, Herman F. F. Egberink, Arjan Stegeman, Nadia Oreshkova, Wim H. M. van der Poel, Mart C. M. de Jong
Summary: This study shows that domestic cats can be infected with SARS-CoV-2 through direct and indirect contact with infected cats or contaminated environments. The transmission rate between cats is efficient, but the infectiousness of a contaminated environment decays rapidly.
MICROBIOLOGY SPECTRUM
(2023)
Article
Infectious Diseases
Camilla Smoglica, Simone Angelucci, Fabrizia Di Tana, Antonio Antonucci, Fulvio Marsilio, Cristina Esmeralda Di Francesco
Summary: The Apennine wolf, a subspecies of gray wolf, experienced a population decline in the past but has been restored through conservation efforts. However, antibiotic-resistant bacteria found in these wolves pose a threat to their health, as well as the health of other animals in their environment. A study conducted in Italy investigated the antibiotic resistance profiles of bacteria collected from Apennine wolves, revealing the presence of multidrug-resistant bacteria to critically important antibiotics. These findings offer insights into antibiotic resistance in wildlife and its implications for biodiversity conservation and public health.
Review
Virology
Severine Tasker, Diane D. Addie, Herman Egberink, Regina Hofmann-Lehmann, Margaret J. Hosie, Uwe Truyen, Sandor Belak, Corine Boucraut-Baralon, Tadeusz Frymus, Albert Lloret, Fulvio Marsilio, Maria Grazia Pennisi, Etienne Thiry, Karin Moestl, Katrin Hartmann
Summary: Feline coronavirus (FCoV) is a common virus in cats that is primarily transmitted faeco-orally. While most infections do not cause clinical signs, a small proportion of infected cats develop feline infectious peritonitis (FIP), which is most frequently seen in cats under two years old. Cats with FIP typically present with fever, anorexia, weight loss, and effusions.
Review
Virology
Katrin Hartmann, Herman Egberink, Karin Moestl, Diane D. Addie, Sandor Belak, Corine Boucraut-Baralon, Tadeusz Frymus, Albert Lloret, Regina Hofmann-Lehmann, Fulvio Marsilio, Maria Grazia Pennisi, Severine Tasker, Etienne Thiry, Uwe Truyen, Margaret J. Hosie
Summary: Vaccine-associated adverse events (VAAEs), such as feline injection-site sarcomas (FISSs), are rare but can be severe. The European Advisory Board on Cat Diseases (ABCD) provides a comprehensive review on VAAEs in cats, summarizing existing knowledge and filling gaps with expert opinions. The causes of VAAEs include immune reactions, local reactions, administration errors, and manufacturing failures. FISS, the most severe VAAE, can occur after vaccinations or other injections. It is important to understand and minimize the risks associated with vaccination.
Review
Virology
Maria Grazia Pennisi, Sandor Belak, Severine Tasker, Diane D. Addie, Corine Boucraut-Baralon, Herman Egberink, Tadeusz Frymus, Katrin Hartmann, Regina Hofmann-Lehmann, Albert Lloret, Fulvio Marsilio, Etienne Thiry, Uwe Truyen, Karin Moestl, Margaret J. Hosie
Summary: Feline morbillivirus (FeMV) is a virus associated with feline chronic kidney disease (CKD) and has a worldwide distribution. The genetic diversity of FeMV is extensive, but its clinical relevance is still unknown. There is conflicting evidence regarding the association between FeMV infection and renal disease. Higher viral loads are found in urine and are associated with renal TIN lesions.
Article
Virology
Mirjam B. H. M. Duijvestijn, Nancy N. M. P. Schuurman, Johannes C. M. Vernooij, Michelle A. J. M. van Leeuwen, Berend-Jan Bosch, Judith M. A. van den Brand, Jaap A. A. Wagenaar, Frank J. M. van Kuppeveld, Herman F. F. Egberink, Josanne H. H. Verhagen
Summary: This study investigated the prevalence of viral pathogens in stray cats living in rural areas in The Netherlands. The results showed that stray cats could host feline leukemia virus (FeLV), feline coronavirus (FCoV), and suspected SARS-CoV-2 infections, but the risk of FeLV transmission was low. Additionally, there was no evidence of SARS-CoV-2 cat-to-cat spread, indicating a low likelihood of spillover to humans.
Article
Infectious Diseases
Camilla Smoglica, Muhammad Farooq, Fausto Ruffini, Fulvio Marsilio, Cristina Esmeralda Di Francesco
Summary: This study compared the microbiome composition and abundance of antimicrobial resistance genes in broiler litter samples from conventional and antibiotic-free flocks. The results suggest that antibiotic use can influence the frequency of resistance determinants and the microbial community in poultry flocks.
Article
Infectious Diseases
Camilla Smoglica, Lisa Barco, Simone Angelucci, Massimiliano Orsini, Fulvio Marsilio, Antonio Antonucci, Cristina Esmeralda Di Francesco
Summary: This pilot study used ecological data, microbiological investigations, and whole genome sequencing to characterize genetic patterns of antimicrobial resistance in bacterial isolates from domestic and wild ruminants in Maiella National Park, Italy. The analyzed isolates showed resistance to important antibiotics and virulence genes. This study provides new data on bacteria from rare and endangered species and contributes to understanding the transmission of antimicrobial resistance and virulence factors.
JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE
(2023)