REST and CoREST are transcriptional and epigenetic regulators of seminal neural fate decisions

Impact of nuclear organization and dynamics on epigenetic regulation in the central nervous system: implications for neurological disease states

(2010) Irfan A. Qureshi et al.   Annals of the New York Academy of Sciences

Mosaic expression of Med12 in female mice leads to exencephaly, spina bifida, and craniorachischisis

(2010) Pedro P. Rocha et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation

(2010) Tim R Mercer et al.   BMC NEUROSCIENCE

Long non-coding RNAs in nervous system function and disease

(2010) Irfan A. Qureshi et al.   BRAIN RESEARCH

MicroRNA Gene Regulatory Pathways in the Establishment and Maintenance of ESC Identity

(2010) Natalia J. Martinez et al.   Cell Stem Cell

Rest Promotes the Early Differentiation of Mouse ESCs but Is Not Required for Their Maintenance

(2010) Yasuhiro Yamada et al.   Cell Stem Cell

The transcriptional repressor REST/NRSF modulates hedgehog signaling

(2010) Keith P. Gates et al.   DEVELOPMENTAL BIOLOGY

MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output

(2010) Lihong Chen et al.   EMBO JOURNAL

BMP-induced REST regulates the establishment and maintenance of astrocytic identity

(2010) Jun Kohyama et al.   JOURNAL OF CELL BIOLOGY

Lysine-Specific Demethylase 1 Regulates the Embryonic Transcriptome and CoREST Stability

(2010) C. T. Foster et al.   MOLECULAR AND CELLULAR BIOLOGY

Can controversies be put to REST?

(2010) Helle F. Jørgensen et al.   NATURE

Mediator and cohesin connect gene expression and chromatin architecture

(2010) Michael H. Kagey et al.   NATURE

Epigenetic control of neural precursor cell fate during development

(2010) Yusuke Hirabayashi et al.   NATURE REVIEWS NEUROSCIENCE

Roles of small regulatory RNAs in determining neuronal identity

(2010) Xuekun Li et al.   NATURE REVIEWS NEUROSCIENCE

The role of REST in transcriptional and epigenetic dysregulation in Huntington's disease

(2010) Noel J. Buckley et al.   NEUROBIOLOGY OF DISEASE

Bmi-1 regulates self-renewal, proliferation and senescence of human fetal neural stem cells in vitro

(2010) Yang Wang et al.   NEUROSCIENCE LETTERS

Regulation of protocadherin gene expression by multiple neuron-restrictive silencer elements scattered in the gene cluster

(2010) Yuen-Peng Tan et al.   NUCLEIC ACIDS RESEARCH

Corepressor for element-1-silencing transcription factor preferentially mediates gene networks underlying neural stem cell fate decisions

(2010) J. J. Abrajano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation

(2010) O. M. Dovey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex

(2010) J. D. Pereira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

The human Mediator complex: a versatile, genome-wide regulator of transcription

(2010) Dylan J. Taatjes   TRENDS IN BIOCHEMICAL SCIENCES

The molecular and gene regulatory signature of a neuron

(2010) Oliver Hobert et al.   TRENDS IN NEUROSCIENCES

RNA regulation of epigenetic processes

(2009) John S. Mattick et al.   BIOESSAYS

A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death

(2009) Kaoru Saijo et al.   CELL

REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells

(2009) H. F. Jorgensen et al.   DEVELOPMENT

Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level

(2009) A. W. Bruce et al.   GENOME RESEARCH

DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down syndrome

(2009) Aude-Marie Lepagnol-Bestel et al.   HUMAN MOLECULAR GENETICS

Further clinical and molecular delineation of the 9q subtelomeric deletion syndrome supports a major contribution of EHMT1 haploinsufficiency to the core phenotype

(2009) T Kleefstra et al.   JOURNAL OF MEDICAL GENETICS

The Bifunctional microRNA miR-9/miR-9* Regulates REST and CoREST and Is Downregulated in Huntington's Disease

(2009) A. N. Packer et al.   JOURNAL OF NEUROSCIENCE

Is REST required for ESC pluripotency?

(2009) Helle F. Jørgensen et al.   NATURE

Is REST a regulator of pluripotency?

(2009) Noel J. Buckley et al.   NATURE

Orphan nuclear receptor TLX activates Wnt/β-catenin signalling to stimulate neural stem cell proliferation and self-renewal

(2009) Qiuhao Qu et al.   NATURE CELL BIOLOGY

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

(2009) Paul A Northcott et al.   NATURE GENETICS

A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination

(2009) Chunnian Zhao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Control of Cognition and Adaptive Behavior by the GLP/G9a Epigenetic Suppressor Complex

(2009) Anne Schaefer et al.   NEURON

Regulation of non-coding RNA networks in the nervous system—What's the REST of the story?

(2009) Irfan A. Qureshi et al.   NEUROSCIENCE LETTERS

Differential Deployment of REST and CoREST Promotes Glial Subtype Specification and Oligodendrocyte Lineage Maturation

(2009) Joseph J. Abrajano et al.   PLoS One

REST and CoREST Modulate Neuronal Subtype Specification, Maturation and Maintenance

(2009) Joseph J. Abrajano et al.   PLoS One

Impairment of developmental stem cell-mediated striatal neurogenesis and pluripotency genes in a knock-in model of Huntington's disease

(2009) A. E. Molero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

(2009) Ahmad M. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells

(2009) J. Sheik Mohamed et al.   RNA

Genomic and Transcriptional Co-Localization of Protein-Coding and Long Non-Coding RNA Pairs in the Developing Brain

(2009) Jasmina Ponjavic et al.   PLoS Genetics

Profiling RE1/REST-mediated histone modifications in the human genome

(2009) Deyou Zheng et al.   GENOME BIOLOGY

A Homozygous Mutation in Human PRICKLE1 Causes an Autosomal-Recessive Progressive Myoclonus Epilepsy-Ataxia Syndrome

(2008) Alexander G. Bassuk et al.   AMERICAN JOURNAL OF HUMAN GENETICS

DYRK1A-Dosage Imbalance Perturbs NRSF/REST Levels, Deregulating Pluripotency and Embryonic Stem Cell Fate in Down Syndrome

(2008) Claudia Canzonetta et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network

(2008) E. Dessaud et al.   DEVELOPMENT

Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation

(2008) M. E. Dinger et al.   GENOME RESEARCH

Epigenetic regulation of stem cell fate

(2008) V. V. Lunyak et al.   HUMAN MOLECULAR GENETICS

MED19 and MED26 Are Synergistic Functional Targets of the RE1 Silencing Transcription Factor in Epigenetic Silencing of Neuronal Gene Expression

(2008) Ning Ding et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Dynamically Regulated MicroRNA and mRNA Networks in Developing Oligodendrocytes

(2008) P. Lau et al.   JOURNAL OF NEUROSCIENCE

Transrepressive Function of TLX Requires the Histone Demethylase LSD1

(2008) A. Yokoyama et al.   MOLECULAR AND CELLULAR BIOLOGY

Mediator Links Epigenetic Silencing of Neuronal Gene Expression with X-Linked Mental Retardation

(2008) Ning Ding et al.   MOLECULAR CELL

CDYL Bridges REST and Histone Methyltransferases for Gene Repression and Suppression of Cellular Transformation

(2008) Peter Mulligan et al.   MOLECULAR CELL

REST maintains self-renewal and pluripotency of embryonic stem cells

(2008) Sanjay K. Singh et al.   NATURE

SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation

(2008) Thomas F. Westbrook et al.   NATURE

Control of chromosome stability by the β-TrCP–REST–Mad2 axis

(2008) Daniele Guardavaccaro et al.   NATURE

Regulatory networks define phenotypic classes of human stem cell lines

(2008) Franz-Josef Müller et al.   NATURE

Rest-Mediated Regulation of Extracellular Matrix Is Crucial for Neural Development

(2008) Yuh-Man Sun et al.   PLoS One

Specific expression of long noncoding RNAs in the mouse brain

(2008) T. R. Mercer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of neural macroRNAs by the transcriptional repressor REST

(2008) R. Johnson et al.   RNA

REST Regulates Distinct Transcriptional Networks in Embryonic and Neural Stem Cells

(2008) Rory Johnson et al.   PLOS BIOLOGY

Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains

(2008) Manching Ku et al.   PLoS Genetics

A microRNA-based gene dysregulation pathway in Huntington's disease

(2007) Rory Johnson et al.   NEUROBIOLOGY OF DISEASE