Mechanisms of non-apoptotic programmed cell death in diabetes and heart failure

Cell Death in the Pathogenesis of Heart Disease: Mechanisms and Significance

(2010) Russell S. Whelan et al.   Annual Review of Physiology

Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy

(2010) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting cyclophilin D and the mitochondrial permeability transition enhances  -cell survival and prevents diabetes in Pdx1 deficiency

(2010) K. Fujimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletion of Fas in the pancreatic β-cells leads to enhanced insulin secretion

(2009) Diana Choi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Role of sarcoplasmic reticulum in mitochondrial permeability transition and cardiomyocyte death during reperfusion

(2009) Marisol Ruiz-Meana et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The role of the mitochondrial permeability transition pore in heart disease

(2009) Andrew P. Halestrap et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Bad News for  -Cell Apoptosis

(2009) H. E. Thomas et al.   DIABETES

The mitochondrial permeability transition pore in motor neurons: Involvement in the pathobiology of ALS mice

(2009) Lee J. Martin et al.   EXPERIMENTAL NEUROLOGY

Autophagy Regulates Pancreatic Beta Cell Death in Response to Pdx1 Deficiency and Nutrient Deprivation

(2009) Kei Fujimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Local control of mitochondrial membrane potential, permeability transition pore and reactive oxygen species by calcium and calmodulin in rat ventricular myocytes

(2009) Keiichi Odagiri et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitochondrial Permeability Transition Pore Opening as a Promising Therapeutic Target in Cardiac Diseases

(2009) S. Javadov et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The role of inflammation in insulitis and β-cell loss in type 1 diabetes

(2009) Décio L. Eizirik et al.   Nature Reviews Endocrinology

Cardiac reanimation: targeting cardiomyocyte death by BNIP3 and NIX/BNIP3L

(2009) G W Dorn et al.   ONCOGENE

Apoptotic and non-apoptotic programmed cardiomyocyte death in ventricular remodelling

(2008) G. W. Dorn   CARDIOVASCULAR RESEARCH

Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway

(2008) Junichi Hitomi et al.   CELL

Nix-Mediated Apoptosis Links Myocardial Fibrosis, Cardiac Remodeling, and Hypertrophy Decompensation

(2008) Abhinav Diwan et al.   CIRCULATION

pdx-1 function is specifically required in embryonic β cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis

(2008) Maureen Gannon et al.   DEVELOPMENTAL BIOLOGY

Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy

(2008) Douglas P Millay et al.   NATURE MEDICINE

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

(2008) Heng Du et al.   NATURE MEDICINE

The genetics of the p53 pathway, apoptosis and cancer therapy

(2008) Alexei Vazquez et al.   NATURE REVIEWS DRUG DISCOVERY

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY