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How do real tumors become resistant to cisplatin?

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Sensitivity and Acquired Resistance of BRCA1;p53-Deficient Mouse Mammary Tumors to the Topoisomerase I Inhibitor Topotecan

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A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

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High Incidence of Protein-Truncating TP53 Mutations in BRCA1-Related Breast Cancer

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Separating Stem Cells by Flow Cytometry: Reducing Variability for Solid Tissues

(2009) Caroline M. Alexander et al.   Cell Stem Cell

Adhesion within the stem cell niches

(2009) Karine Raymond et al.   CURRENT OPINION IN CELL BIOLOGY

Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis

(2009) Jane E. Visvader   GENES & DEVELOPMENT

Sensitivity to First-Line Chemotherapy for Metastatic Breast Cancer inBRCA1andBRCA2Mutation Carriers

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The DNA-damage response in human biology and disease

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Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

(2009) Elgene Lim et al.   NATURE MEDICINE

MMTV-Wnt1 and -ΔN89β-Catenin Induce Canonical Signaling in Distinct Progenitors and Differentially Activate Hedgehog Signaling within Mammary Tumors

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Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

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The Increasing Complexity of the Cancer Stem Cell Paradigm

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Roles of Integrins in Human Induced Pluripotent Stem Cell Growth on Matrigel and Vitronectin

(2009) Teisha J. Rowland et al.   STEM CELLS AND DEVELOPMENT

Cancer Stem Cells Contribute to Cisplatin Resistance in Brca1/p53-Mediated Mouse Mammary Tumors

(2008) N. Shafee et al.   CANCER RESEARCH

Secondary BRCA1 Mutations in BRCA1-Mutated Ovarian Carcinomas with Platinum Resistance

(2008) E. M. Swisher et al.   CANCER RESEARCH

Transcriptome Analysis of the Normal Human Mammary Cell Commitment and Differentiation Process

(2008) Afshin Raouf et al.   Cell Stem Cell

Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy

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Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers

(2008) Wataru Sakai et al.   NATURE

Resistance to therapy caused by intragenic deletion in BRCA2

(2008) Stacey L. Edwards et al.   NATURE

Efficient tumour formation by single human melanoma cells

(2008) Elsa Quintana et al.   NATURE

β1 Integrin deletion from the basal compartment of the mammary epithelium affects stem cells

(2008) Ilaria Taddei et al.   NATURE CELL BIOLOGY

A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability

(2008) Peter Eirew et al.   NATURE MEDICINE

Regulation of DNA repair throughout the cell cycle

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Isolation and Molecular Characterization of Cancer Stem Cells in MMTV-Wnt-1Murine Breast Tumors

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