Centriole duplication

Centrioles: active players or passengers during mitosis?

(2010) Alain Debec et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability

(2010) Andrew J. Holland et al.   JOURNAL OF CELL BIOLOGY

Plk4 is required for cytokinesis and maintenance of chromosomal stability

(2010) C. O. Rosario et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Degradation of Activated Protein Kinases by Ubiquitination

(2009) Lu Zhimin et al.   Annual Review of Biochemistry

Cullin 1 Functions as a Centrosomal Suppressor of Centriole Multiplication by Regulating Polo-like Kinase 4 Protein Levels

(2009) N. Korzeniewski et al.   CANCER RESEARCH

Centrioles, Centrosomes, and Cilia in Health and Disease

(2009) Erich A. Nigg et al.   CELL

The SCFSlimbubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication

(2009) Gregory C. Rogers et al.   JOURNAL OF CELL BIOLOGY

Autophosphorylation of Polo-like Kinase 4 and Its Role in Centriole Duplication

(2009) James E. Sillibourne et al.   MOLECULAR BIOLOGY OF THE CELL

Ab ovo or de novo? Mechanisms of centriole duplication

(2009) Jadranka Loncarek et al.   MOLECULES AND CELLS

A mechanism linking extra centrosomes to chromosomal instability

(2009) Neil J. Ganem et al.   NATURE

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

(2009) Andrew J. Holland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multipolar Spindle Pole Coalescence Is a Major Source of Kinetochore Mis-Attachment and Chromosome Mis-Segregation in Cancer Cells

(2009) William T. Silkworth et al.   PLoS One

Beyond Genetics: Surprising Determinants of Cell Fate in Antitumor Drugs

(2008) Andrew J. Holland et al.   CANCER CELL

Cancer Cells Display Profound Intra- and Interline Variation following Prolonged Exposure to Antimitotic Drugs

(2008) Karen E. Gascoigne et al.   CANCER CELL

Centrosome Amplification Can Initiate Tumorigenesis in Flies

(2008) Renata Basto et al.   CELL

The SCF/Slimb Ubiquitin Ligase Limits Centrosome Amplification through Degradation of SAK/PLK4

(2008) Inês Cunha-Ferreira et al.   CURRENT BIOLOGY

Examining the link between chromosomal instability and aneuploidy in human cells

(2008) Sarah L. Thompson et al.   JOURNAL OF CELL BIOLOGY

Extra centrosomes and/or chromosomes prolong mitosis in human cells

(2008) Zhenye Yang et al.   NATURE CELL BIOLOGY