An increase in integrin-linked kinase non-canonically confers NF-κB-mediated growth advantages to gastric cancer cells by activating ERK1/2

Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response

(2013) Korana Radovanac et al.   EMBO JOURNAL

Overexpression of Integrin-linked Kinase Promotes Lung Cancer Cell Migration and Invasion via NF-κB-mediated Upregulation of Matrix Metalloproteinase-9

(2013) Mingjing Zhao et al.   International Journal of Medical Sciences

Overexpression of integrin-linked kinase (ILK) promotes glioma cell invasion and migration and down-regulates E-cadherin via the NF-κB pathway

(2013) Feng Liang et al.   JOURNAL OF MOLECULAR HISTOLOGY

IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase–driven tumors

(2013) Katherine L Jameson et al.   NATURE MEDICINE

Replacement treatment with microRNA-143 and -145 induces synergistic inhibition of the growth of human bladder cancer cells by regulating PI3K/Akt and MAPK signaling pathways

(2012) Shunsuke Noguchi et al.   CANCER LETTERS

 -Catulin Drives Metastasis by Activating ILK and Driving an  v 3 Integrin Signaling Axis

(2012) C.-H. Liang et al.   CANCER RESEARCH

Regulation of SHP2 by PTEN/AKT/GSK-3β signaling facilitates IFN-γ resistance in hyperproliferating gastric cancer

(2012) Po-Chun Tseng et al.   IMMUNOBIOLOGY

Global Identification of Modular Cullin-RING Ligase Substrates

(2011) Michael J. Emanuele et al.   CELL

IQGAP1 and its binding proteins control diverse biological functions

(2011) Colin D. White et al.   CELLULAR SIGNALLING

Antiproliferative effect of SOCS-1 through the suppression of STAT3 and p38 MAPK activation in gastric cancer cells

(2011) Yoshihito Souma et al.   INTERNATIONAL JOURNAL OF CANCER

Loss of TFF1 is associated with activation of NF-κB–mediated inflammation and gastric neoplasia in mice and humans

(2011) Mohammed Soutto et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification and Characterization of a Novel Integrin-Linked Kinase Inhibitor

(2011) Su-Lin Lee et al.   JOURNAL OF MEDICINAL CHEMISTRY

Integrin-linked kinase regulates melanoma angiogenesis by activating NF-κB/interleukin-6 signaling pathway

(2011) A A Wani et al.   ONCOGENE

Integrin-linked kinase in gastric cancer cell attachment, invasion and tumor growth

(2011) Gang Zhao   WORLD JOURNAL OF GASTROENTEROLOGY

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

Integrin-Linked Kinase Controls Microtubule Dynamics Required for Plasma Membrane Targeting of Caveolae

(2010) Sara A. Wickström et al.   DEVELOPMENTAL CELL

Heat shock protein 90 maintains the tumour-like character of rheumatoid synovial cells by stabilizing integrin-linked kinase, extracellular signal-regulated kinase and protein kinase B

(2010) A. Hashiramoto et al.   RHEUMATOLOGY

Hsp90 and co-chaperones twist the functions of diverse client proteins

(2009) Abbey Zuehlke et al.   BIOPOLYMERS

Type I collagen promotes epithelial–mesenchymal transition through ILK-dependent activation of NF-κB and LEF-1

(2009) Damian Medici et al.   MATRIX BIOLOGY

Combination of EGFR and MEK1/2 inhibitor shows synergistic effects by suppressing EGFR/HER3-dependent AKT activation in human gastric cancer cells

(2009) Y.-K. Yoon et al.   MOLECULAR CANCER THERAPEUTICS

The regulation of extracellular signal-regulated kinase (ERK) in mammalian cells

(2008) Joe W. Ramos   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Helicobacter pyloriVacA-induced Inhibition of GSK3 through the PI3K/Akt Signaling Pathway

(2008) Masaaki Nakayama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin-linked kinase - essential roles in physiology and cancer biology

(2008) P. C. McDonald et al.   JOURNAL OF CELL SCIENCE

Mapping the Integrin-Linked Kinase Interactome Using SILAC

(2008) Iveta Dobreva et al.   JOURNAL OF PROTEOME RESEARCH

Combined analysis of Rac1, IQGAP1, Tiam1 and E-cadherin expression in gastric cancer

(2008) Axel Walch et al.   MODERN PATHOLOGY