INPP4B suppresses prostate cancer cell invasion

INPP4B: the New Kid on the PI3K Block

(2015) Irina U. Agoulnik et al.   Oncotarget

CCL2 Is a Negative Regulator of AMP-Activated Protein Kinase to Sustain mTOR Complex-1 Activation, Survivin Expression, and Cell Survival in Human Prostate Cancer PC3 Cells

(2015) Hernan Roca et al.   NEOPLASIA

Activation of Pro-uPA Is Critical for Initial Escape from the Primary Tumor and Hematogenous Dissemination of Human Carcinoma Cells

(2015) Erin M. Bekes et al.   NEOPLASIA

Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities

(2013) Sandra M. Lopez et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

High Fidelity Patient-Derived Xenografts for Accelerating Prostate Cancer Discovery and Drug Development

(2013) D. Lin et al.   CANCER RESEARCH

Src-dependent Tks5 phosphorylation regulates invadopodia-associated invasion in prostate cancer cells

(2013) Karen L. Burger et al.   PROSTATE

Promising Noninvasive Cellular Phenotype in Prostate Cancer Cells Knockdown of Matrix Metalloproteinase 9

(2013) Aditi Gupta et al.   TheScientificWorldJOURNAL

Potentiation of Inflammatory CXCL8 Signalling Sustains Cell Survival in PTEN-deficient Prostate Carcinoma

(2012) Pamela J. Maxwell et al.   EUROPEAN UROLOGY

p21-activated Kinase 6 (PAK6) Inhibits Prostate Cancer Growth via Phosphorylation of Androgen Receptor and Tumorigenic E3 Ligase Murine Double Minute-2 (Mdm2)

(2012) Tong Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diversity of Antigen-Specific Responses Induced In Vivo with CTLA-4 Blockade in Prostate Cancer Patients

(2012) S. S. Kwek et al.   JOURNAL OF IMMUNOLOGY

Protein Kinase C Inhibitor AEB071 Targets Ocular Melanoma Harboring GNAQ Mutations via Effects on the PKC/Erk1/2 and PKC/NF- B Pathways

(2012) X. Wu et al.   MOLECULAR CANCER THERAPEUTICS

The mutational landscape of lethal castration-resistant prostate cancer

(2012) Catherine S. Grasso et al.   NATURE

The Protein Kinase C Inhibitor Enzastaurin Exhibits Antitumor Activity against Uveal Melanoma

(2012) Xinqi Wu et al.   PLoS One

Decreased Expression and Androgen Regulation of the Tumor Suppressor Gene INPP4B in Prostate Cancer

(2011) Myles C. Hodgson et al.   CANCER RESEARCH

Genetic Ablation of PKC Epsilon Inhibits Prostate Cancer Development and Metastasis in Transgenic Mouse Model of Prostate Adenocarcinoma

(2011) B. B. Hafeez et al.   CANCER RESEARCH

Inositol Polyphosphate 4-Phosphatase B as a Regulator of Bone Mass in Mice and Humans

(2011) Mathieu Ferron et al.   Cell Metabolism

The functional role of reactive stroma in benign prostatic hyperplasia

(2011) Isaiah G. Schauer et al.   DIFFERENTIATION

Androgen receptor footprint on the way to prostate cancer progression

(2011) Myles C. Hodgson et al.   WORLD JOURNAL OF UROLOGY

IAP Regulation of Metastasis

(2010) Swarna Mehrotra et al.   CANCER CELL

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

Targeting MMP-9, uPAR and cathepsin B inhibits invasion, migration and activates apoptosis in prostate cancer cells

(2010) A K Nalla et al.   CANCER GENE THERAPY

Protein kinase Cɛ mediates Stat3Ser727 phosphorylation, Stat3-regulated gene expression and cell invasion in various human cancer cell lines through integration with MAPK cascade (RAF-1, MEK1/2 and ERK1/2)

(2010) M H Aziz et al.   ONCOGENE

Analysis of Kinase Gene Expression Patterns across 5681 Human Tissue Samples Reveals Functional Genomic Taxonomy of the Kinome

(2010) Sami Kilpinen et al.   PLoS One

Comparative Analysis of Metastasis Variants Derived from Human Prostate Carcinoma Cells

(2009) Erin M. Conn et al.   AMERICAN JOURNAL OF PATHOLOGY

Evidence that Inositol Polyphosphate 4-Phosphatase Type II Is a Tumor Suppressor that Inhibits PI3K Signaling

(2009) Christina Gewinner et al.   CANCER CELL

Disseminated Tumor Cells in Prostate Cancer Patients after Radical Prostatectomy and without Evidence of Disease Predicts Biochemical Recurrence

(2009) T. M. Morgan et al.   CLINICAL CANCER RESEARCH

Identification of the Transcription Factor Single-Minded Homologue 2 as a Potential Biomarker and Immunotherapy Target in Prostate Cancer

(2009) M. S. Arredouani et al.   CLINICAL CANCER RESEARCH

Perioperative Activation of Disseminated Tumor Cells in Bone Marrow of Patients With Prostate Cancer

(2009) Dorothea Weckermann et al.   JOURNAL OF CLINICAL ONCOLOGY

ASAP1, a Gene at 8q24, Is Associated with Prostate Cancer Metastasis

(2008) D. Lin et al.   CANCER RESEARCH

Interleukin-8 signaling promotes androgen-independent proliferation of prostate cancer cells via induction of androgen receptor expression and activation

(2008) A. Seaton et al.   CARCINOGENESIS

The Interleukin-8 Pathway in Cancer

(2008) D. J.J. Waugh et al.   CLINICAL CANCER RESEARCH

Chick embryo chorioallantoic membrane model systems to study and visualize human tumor cell metastasis

(2008) Elena I. Deryugina et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Invadopodia and Matrix Degradation, a New Property of Prostate Cancer Cells during Migration and Invasion

(2008) Bhavik Desai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sequential signals toward podosome formation in NIH-src cells

(2008) Tsukasa Oikawa et al.   JOURNAL OF CELL BIOLOGY

Increased PAK6 expression in prostate cancer and identification of PAK6 associated proteins

(2008) Ramneet Kaur et al.   PROSTATE

Keratinocyte-derived chemokine induces prostate epithelial hyperplasia and reactive stroma in a novel transgenic mouse model

(2008) Isaiah G. Schauer et al.   PROSTATE

Elevated Epithelial Expression of Interleukin-8 Correlates with Myofibroblast Reactive Stroma in Benign Prostatic Hyperplasia

(2008) Isaiah G. Schauer et al.   UROLOGY